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Updated: Jun 14, 2026

Long Term Chronic Pseudomonas aeruginosa Airway Infection in Mice

Long Term Chronic Pseudomonas aeruginosa Airway Infection in Mice

Published on: March 17, 2014

Bronchiectasis: an update.

Maria Pappalettera¹, Stefano Aliberti, Paola Castellotti

¹Dipartimento Toraco-Polmonare e Cardiovascolare, University of Milan, Istituti di Ricovero e Cura a Carattere Scientifico Fondazione PoMaRe, Milan, Italy.

The Clinical Respiratory Journal

|March 20, 2010

Summary

This summary is machine-generated.

Bronchiectasis, a condition causing irreversible airway dilation, affects more older adults. Current therapies aim to reduce infections and inflammation, improving quality of life for those with this chronic respiratory disease.

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Last Updated: Jun 14, 2026

Long Term Chronic Pseudomonas aeruginosa Airway Infection in Mice

Long Term Chronic Pseudomonas aeruginosa Airway Infection in Mice

Published on: March 17, 2014

Area of Science:

Pulmonology
Respiratory Medicine

Background:

Bronchiectasis is characterized by irreversible bronchial dilation, leading to chronic cough, airway obstruction, and recurrent infections.
The exact prevalence of bronchiectasis is not fully established but appears to increase significantly with age.

Purpose of the Study:

To review the current understanding and management of bronchiectasis.
To highlight the need for further research into this heterogeneous respiratory condition.

Main Methods:

A comprehensive literature search was conducted using MEDLINE from 1978 to November 2008.
The search was restricted to randomized controlled trials, clinical trials, meta-analyses, and reviews published in English, using the keyword "bronchiectasis".

Main Results:

Prevalence data indicates a marked increase with age, from 4.2 per 100,000 in young adults to 271.8 per 100,000 in individuals aged 75 and older.
Therapeutic strategies focus on interrupting the cycle of infection and inflammation to decrease exacerbations and enhance patient quality of life.

Conclusions:

Bronchiectasis remains a significant public health concern.
Improved management strategies are needed for this complex and varied condition, necessitating further research.