Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Brain abscess in childhood--long-term experiences.

C Aebi1, F Kaufmann, U B Schaad

  • 1Department of Paediatrics, University of Berne, Inselspital, Switzerland.

European Journal of Pediatrics
|February 1, 1991
PubMed
Summary

Paediatric brain abscess treatment has evolved, with CT scans significantly reducing diagnostic delays and mortality. Surgical excision is linked to worse outcomes, favoring antibiotics and needle aspiration.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A comparison of bronchoalveolar lavage and gastric aspirate for diagnosis of paediatric TB.

The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease·2023
Same author

Corticosterone in feathers of laying hens: an assay validation for evidence-based assessment of animal welfare.

Poultry science·2020
Same author

Avoidance of Outflow Graft Extrinsic Compression in Polytetrafluoroethylene Reinforcements of the Bend Relief Component.

The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation·2019
Same author

Effect of pH-lowering litter amendment on animal-based welfare indicators and litter quality in a European commercial broiler husbandry.

Poultry science·2018
Same author

Unilesional plantar mycosis fungoides treated with topical photodynamic therapy - case report and review of the literature.

Journal of the European Academy of Dermatology and Venereology : JEADV·2017
Same author

Impaired antibody memory to varicella zoster virus in HIV-infected children: low antibody levels and avidity*.

HIV medicine·2011

Area of Science:

  • Pediatric Neurology
  • Neurosurgery
  • Infectious Diseases

Background:

  • Paediatric brain abscesses are rare but serious infections.
  • Historically, predisposing factors included congenital heart disease, sinusitis, otitis media, mastoiditis, and immunodeficiency.
  • Non-specific symptoms often delayed diagnosis and treatment.

Purpose of the Study:

  • To evaluate treatment outcomes for paediatric brain abscesses.
  • To assess the impact of diagnostic imaging, specifically CT scans, on patient outcomes.
  • To compare the long-term sequelae associated with different surgical interventions.

Main Methods:

  • Retrospective analysis of 28 paediatric brain abscess cases diagnosed between 1967 and 1987.
  • Review of predisposing factors, clinical presentation, diagnostic methods, and treatment approaches.
  • Long-term follow-up assessments including neurological examinations, EEG, and psychological testing.

Main Results:

  • CT availability reduced diagnostic delay from 8.4 to 3.0 days and mortality from 23% to 0%.
  • Long-term sequelae included neurological deficits (35%), epilepsy (29%), and CNS scars (50%).
  • Surgical excision was associated with higher rates of CNS scars and epilepsy compared to aspiration and antibiotics.

Conclusions:

  • CT scans have dramatically improved paediatric brain abscess management.
  • Surgical excision of brain abscesses should be avoided due to increased long-term complications.
  • Optimal treatment involves antibiotics, potentially with CT-guided needle aspiration.

Related Experiment Videos