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Updated: Jun 14, 2026

Murine Bilateral Renal Lymphadenectomy
Published on: December 30, 2025
[Acute renal failure caused by renal lymphoma. A case report]
Imen Gorsane1, Latifa Bourkhis, Mohamed Adnène Laatiri
1Service de néphrologie-dialyse-transplantation rénale, CHU F. Bourguiba, rue 1er-Juin, CP : 5000, Monastir, Tunisie. imen_gorsane@voila.fr
Abstract:
Acute renal failure, as the initial manifestation of lymphoma, has been reported only in a few cases. In this work, we report the case of a 28-year-old women admitted for acute renal failure. Her physical examination detected bilateral kidney enlargement. Laboratory evaluation revealed a serum creatinine value 218 micromol/l. A 24-hour urine collection analysis allowed the detection of 1g of protein. No red cells were found after urinanalysis. Renal ultrasound showed massively enlarged kidneys. Renal biopsy of the kidney and pathologic examination showed diffuse infiltration of the interstitium with lymphocytes and atypical cells positive for CD20 markers. A diagnosis of diffuse large B-cell type non-Hodgkin lymphoma was made. However, investigations revealed the presence of two others sites of lymphoma: gastric and ophthalmic. The patient's renal function and kidney size as well as the other lymphoma locations were normalized after the initiation of chemotherapy.
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