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Mitomycin C does not inhibit exacerbation of granular corneal dystrophy type II induced by refractive surface
Byoung Jin Ha1, Tae-im Kim, Seung-il Choi
1Siloam Eye Hospital, Seoul, Korea.
Purpose:
To evaluate the effect of mitomycin C (MMC) on the exacerbation of corneal opacity that occurs in patients with granular corneal dystrophy type II (GCD II) after refractive corneal surface ablation.
Methods:
Ten eyes of patients with GCD II who underwent refractive corneal surface ablation with MMC were compared with 10 eyes that were not treated with MMC. Best spectacle-corrected visual acuity, the degree of corneal opacity, and contrast sensitivity were evaluated at least 3 years after surgery. Corneal opacities were quantified using Pentacam densitometry maps.
Results:
No measured between-group value showed a statistically significant difference.
Conclusion:
Simultaneous application of MMC does not prevent exacerbation of GCD II after refractive corneal surface ablation.
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