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An Ex vivo Assay to Study Candida albicans Hyphal Morphogenesis in the Gastrointestinal Tract
Published on: July 1, 2020
The rise of an opportunistic infection called "Invasive Zygomycosis"
Abdelkarim Waness1, Ghuzayel Al Dawsari, Hamdan Al Jahdali
1Department of Internal Medicine, King Abdulaziz Medical City, Riyadh, Saudi Arabia.
Abstract:
Invasive zygomycosis is a devastating fungal infection seen mostly in immune-compromised patients. We present a case of a 48-year old diabetic man, with aplastic anemia, who developed severe pulmonary mucormycosis that led to his rapid demise despite early diagnosis and treatment with liposomal amphotericin B. We also conducted an extensive review of the pathogenesis of invasive zygomycosis, its history, predisposing factors, clinical aspects, diagnostic modalities, treatment options, morbidity and mortality.
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