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Published on: May 6, 2013
Orthotopic Liver Transplantation: Is There a Risk for Listeria monocytogenes Infection?
Urs Ehehalt1, Stefan Schmiedel, Ansgar W Lohse
1Medical Department I (Gastroenterology, Hepatology, Infectious Diseases), University Medical Center Hamburg-Eppendorf, Martinistr. 52, 20246 Hamburg, Germany.
Abstract:
Immunosuppression of any kind is a known risk factor for infection with Listeria monocytogenes (L. monocytogenes). Particularly, patients with impaired liver function are at increased risk of developing an aggravated course of infection with this bacterial pathogen (see Nolla-Salas et al.; 2002 and Cabellos et al.; 2008). It is a well-known pathogen in immunocompromised patients, but has only seldom been reported following orthotopic liver transplantation. Invasion of the central nervous system presenting as meningitis or meningoencephalitis and bacteremia are the principal clinical manifestations of listerial infections (see Brouwer et al.; 2006). We present an account of a case of a patient who developed L. monocytogenes meningitis during the early period after liver transplantation.
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