Effect of submaximal physical exercise on antioxidative protection of human blood platelets

The study was performed on healthy volunteers subjected to submaximal physical exercise (75% VO2max). Activities of catalase (CT) (EC 1.11.1.6), glutathione peroxidase (GPO) (EC 1.11.1.9), superoxide dismutase (ZnCu-SOD) (EC 1.15.1.1) and malonyldialdehyde (MDA) concentration in blood platelets before and after physical exercise were estimated. Physical exercise was found to induce a significant increase in the blood platelet enzymes activity accompanied by lowering platelet MDA concentration and platelet aggregability. The obtained results suggest that physical exercise has some effect on platelet reactivity and on platelet antioxidative enzymes.