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Updated: Jun 14, 2026

Surgical Porcine Model of Chronic Myocardial Ischemia Treated by Exosome-laden Collagen Patch and Off-pump Coronary Artery Bypass Graft
Published on: September 15, 2023
Off-pump coronary artery bypass surgery can be completed safely in high risk patients
Hayrettin Tekumit1, Ali Riza Cenal, Cenk Tataroglu
1Avrupa Safak Hospital, Istanbul, Turkey.
Background:
Off-pump coronary artery bypass (OPCAB) grafting has the potential to reduce morbidity and mortality, compared to on-pump cardiac surgery.
Aim:
We compared the early results of OPCAB lateral and posterior wall revascularisations in 'low', 'intermediate' and 'high' risk patients as defined by the EuroSCORE system.
Methods:
Eighty-nine patients who underwent OPCAB with lateral and posterior wall revascularisation from January 2006 to December 2008 were included in this study. Patients were allocated to one of the three risk groups according to the EuroSCORE system: low, moderate and high risk groups. Perioperative and early postoperative results of the three groups were compared.
Results:
Significantly fewer patients required prolonged ICU stay in the low risk group, compared to moderate (19.4 vs. 50%) and high risk groups (19.4 vs. 36.7%). In addition, prolonged mechanical ventilation was more common in moderate (39.3 vs. 9.7%) and high risk groups (36.7 vs. 9.7%), compared to the low risk group. However, the groups did not differ in terms of mortality or other perioperative outcomes.
Conclusions:
Our results suggest that in patients who are considered high risk on the basis of the EuroSCORE model and have diseased vessels on the lateral and/or posterior walls of the heart suitable for grafting, the early outcomes with OPCAB are similar to those in medium or low EuroSCORE risk category. The EuroSCORE model may overestimate the risk for OPCAB procedures.
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