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[Congenital granular cell epulis: a case report].
1Fingerlandův ústav patologie, Lékarská fakulta UK a Fakultní nemocnice, Hradec Králové. lacoj@lfhk.cuni.cz
Ceskoslovenska Patologie
|March 23, 2010
Summary
Congenital granular cell epulis is a rare newborn lesion. This case report details a female infant with multiple epulis swellings, successfully treated with surgical excision and showing no recurrence.
Area of Science:
- Oral Pathology
- Pediatric Dentistry
- Developmental Biology
Background:
- Congenital granular cell epulis is a rare, benign oral tumor exclusive to newborns.
- It presents as localized swellings on the alveolar mucosa of the maxilla or mandible.
- Etiology remains largely unknown, necessitating case reports for better understanding.
Observation:
- A female newborn presented with multiple, bilateral alveolar swellings up to 10 mm.
- Lesions involved both maxillary and mandibular alveolar mucosa.
- Surgical excision was performed on the 24th postnatal day under general anesthesia.
Findings:
- Microscopic examination confirmed congenital granular cell epulis.
- Immunohistochemistry revealed granular cell expression of vimentin and PGP 9.5.
- S100 protein and inhibin were negative in granular cells.
Implications:
- This case highlights the successful management of congenital granular cell epulis in a neonate.
- The immunohistochemical profile provides further data on the cellular origin of this rare lesion.
- Absence of recurrence after 8 months suggests a favorable prognosis following complete excision.
