Related Experiment Video
Updated: Jun 14, 2026
10:49
Assays for the Specific Growth Rate and Cell-binding Ability of Rotavirus
Published on: January 28, 2019
Australian Rotavirus Surveillance Program annual report, 2008/2009
Carl D Kirkwood1, Karen Boniface, Ruth F Bishop
1National Rotavirus Reference Centre, Murdoch Childrens Research Institute, Royal Children's Hospital, Parkville, Victoria. carl.kirkwood@mcri.edu.au
Communicable Diseases Intelligence Quarterly Report
|March 23, 2010
Summary
Rotavirus surveillance in Australia identified G2P[4] as the dominant strain causing hospitalizations in children. This finding is significant as it
Area of Science:
- Virology
- Epidemiology
- Public Health
Background:
- The Australian Rotavirus Surveillance Program monitors rotavirus strains.
- The study covers the second year post-rotavirus vaccine introduction into the National Immunisation Program.
Purpose of the Study:
- To determine the G and P genotypes of rotavirus strains causing pediatric hospitalizations.
- To describe the epidemiology of rotavirus genotypes in Australia.
Main Methods:
- Laboratory-based surveillance of faecal samples from hospitalized children.
- Hemi-nested multiplex reverse transcription-polymerase chain reaction (RT-PCR) for G and P genotyping.
Main Results:
- G2P[4] was the dominant rotavirus genotype (50.3%), followed by G1P[8] (22.5%).
- Genotypes G3P[8], G4P[8], and G9P[8] were less than 5% nationally.
- An outbreak of severe gastroenteritis linked to G2P[4] occurred in Alice Springs.
Conclusions:
- G2P[4] emerged as the dominant national rotavirus genotype for the first time.
- The emergence of G2P[4] may be linked to an outbreak and warrants further investigation regarding vaccine pressure.
Related Concept Videos
01:18Bacterial Gastroenteritis
Bacterial gastroenteritis, characterized by diarrhea, abdominal cramps, and vomiting, is often caused by ingestion of contaminated food or water and is frequently associated with pathogenic Escherichia coli strains. These microbes exploit two principal mechanisms to inflict disease.Shiga toxin–producing E. coli, also referred to as STEC—notably O157:H7—release Shiga toxins that target ribosomes, blocking protein synthesis. The B subunit of the toxin binds the host glycolipid receptor...
01:03Rous Sarcoma Virus (RSV) and Cancer
Rous Sarcoma virus or RSV was discovered by F. Peyton Rous in the year 1911 as a filterable transmissible agent that could cause tumors in chickens. He won a Nobel Prize for this discovery in 1966. His experiments clearly demonstrated that some cancers could be caused by infectious agents and led to the discovery of many more cancer-causing viruses in animals as well as humans.
RSV is a retrovirus that contains two copies of a plus-strand RNA genome. Its genome consists of four main open...
RSV is a retrovirus that contains two copies of a plus-strand RNA genome. Its genome consists of four main open...
01:26Principles of Disease Surveillance
Disease surveillance is the systematic collection, analysis, and interpretation of health data essential to the planning, implementation, and evaluation of public health practice. This process integrates data dissemination to entities responsible for preventing and controlling disease, injury, and disability. Surveillance systems provide crucial information for action, helping public health authorities make informed decisions to manage and prevent outbreaks, ensure public safety, optimize...