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Intestinal Obstruction I: Introduction

Intestinal Obstruction I: Introduction

Intestinal obstruction is a partial or complete blockage of the small or large intestine that disrupts the normal flow of intestinal contents through the lumen. This interruption impairs digestion, absorption, and fluid balance, and may lead to serious complications if not treated promptly.Mechanical ObstructionMechanical obstruction occurs when a physical blockage prevents intestinal contents from passing, arising from within the lumen or the bowel wall, or from external compression.Adhesions,...

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Intestinal obstruction triggers a series of physiological responses, starting with gas and fluid accumulation in the bowel segment proximal to the obstruction, leading to distension. This distended intestine compresses the diaphragm, hindering lung expansion and potentially leading to reduced respiratory effort, atelectasis, and pneumonia.To overcome the blockage, the gut intensifies contractions, causing colicky abdominal pain, nausea, and vomiting, which reduces fluid and food intake and...

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Pyloric Obstruction

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Related Experiment Video

Updated: Jun 14, 2026

A Mouse Model of Intestinal Partial Obstruction

A Mouse Model of Intestinal Partial Obstruction

Published on: March 5, 2018

Intestinal obstructions: what has changed so far?

Derya Karakoc¹, Alptekin Memis, Iskender Sayek

¹Department of General Surgery, Hacettepe University Medical School, Sihhiye, Ankara, Turkey. Derykarakoc@yahoo.com

International Surgery

|March 23, 2010

Summary

Surgical factors for intestinal obstruction have changed over 20 years, with tumors and peritoneal carcinomatosis becoming more common causes. Diagnostic tools improved, but hospital stay and mortality remained unchanged.

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Last Updated: Jun 14, 2026

A Mouse Model of Intestinal Partial Obstruction

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Published on: March 5, 2018

Postoperative Ileus Murine Model

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Published on: July 12, 2024

Murine Ileocolic Bowel Resection with Primary Anastomosis

Murine Ileocolic Bowel Resection with Primary Anastomosis

Published on: October 29, 2014

Area of Science:

Gastroenterology
Surgical Oncology
Abdominal Surgery

Background:

Intestinal obstruction remains a significant surgical challenge.
Understanding evolving trends in its causes and management is crucial for improving patient outcomes.

Purpose of the Study:

To analyze changes in the factors influencing surgical interventions for intestinal obstruction over two decades.
To identify shifts in etiologies, diagnostic methods, and complications.

Main Methods:

Retrospective analysis of surgical records from 1980-1985 (Group I) and 2000-2005 (Group II).
Comparison of patient demographics, causes of obstruction, diagnostic tools used, and complication rates between the two groups.

Main Results:

A significant shift in the primary cause of intestinal obstruction from adhesions to tumors and peritoneal carcinomatosis was observed (P = 0.0001).
Increased utilization of abdominal computed tomography (CT) in the later period (P = 0.0001).
Higher complication rates were noted in Group II (40.54%) compared to Group I (26.08%) (P = 0.01).

Conclusions:

Intestinal obstruction due to peritoneal carcinomatosis represents a growing clinical problem.
While diagnostic capabilities have advanced, length of hospital stay and mortality rates for intestinal obstruction have not significantly changed over the study period.