Related Experiment Video
Updated: Jun 14, 2026
Murine Model of Leukemia Relapse to Induction Chemotherapy for Acute Lymphoblastic Leukemia
Published on: October 17, 2025
[An epidemiological survey of acute lymphocytic leukemia from 2002 to 2006 in Shanghai.]
Xiong Ni1, Zhi-Xiang Shen, Fang-Yuan Chen
1Departments of Hematology, Shanghai Changhai Hospital, the Second Military Medical University, Shanghai 200433, China.
Objective:
To analyse the epidemiological data of acute lymphoblastic leukemia (ALL) in Shanghai.
Methods:
ALL cases in Shanghai from 2002 to 2006 were retrospectively investigated.
Results:
All together there were 544 newly diagnozed ALL cases. The yearly incidence of ALL was 0.81/10(5), which was slightly higher in men (0.86/10(5)) than in women (0.75/10(5)). The age-stratified incidence showed 2.31/10(5) in patients (pts) 60 y. The incidences in Chongming County was 0.60/10(5), being the lowest in all districts. The morphological types of ALL was L(1) (26.2%), L(2) (57.4%) and L(3) (16.4%); the immunophenotype was B (80.1%) and T (19.5%). The incidence of ALL with myeloid antigen expression was 20.2%. Genetic examination revealed that chromosome aberration of t(9;22) was the most common one.
Conclusions:
The incidence of ALL in Shanghai is 0.81/10(5). Compared with the national standard (1986 - 1998), the incidence in adolescents is obviously increased. Chongming County has the lowest incidence, indicating a role of environment factor in ALL incidence.
