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Related Experiment Video

Updated: Jun 14, 2026

Live-cell Imaging and Quantitative Analysis of Embryonic Epithelial Cells in Xenopus laevis

Live-cell Imaging and Quantitative Analysis of Embryonic Epithelial Cells in Xenopus laevis

Published on: May 23, 2010

Cell adhesion glycoprotein vitronectin during Xenopus laevis embryogenesis.

M E Luque¹, M A Serrano, S M Honoré

¹Instituto Superior de Investigaciones Biológicas (CONICET), Universidad Nacional de Tucumán, Departamento de Biología del Desarrollo, T4000ILI San Miguel de Tucumán, Argentina.

Gene Expression Patterns : GEP

|March 23, 2010

Summary

This study cloned Xenopus laevis vitronectin (vn), revealing its expression during embryonic development. Vitronectin is developmentally regulated and may play a role in embryo organogenesis.

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Last Updated: Jun 14, 2026

Live-cell Imaging and Quantitative Analysis of Embryonic Epithelial Cells in Xenopus laevis

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Published on: May 23, 2010

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Tissue Determination Using the Animal Cap Transplant (ACT) Assay in Xenopus laevis

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Published on: May 16, 2010

Area of Science:

Developmental Biology
Molecular Biology
Comparative Genomics

Background:

Vitronectin (vn) is a crucial cell-adhesive glycoprotein found in vertebrates.
Understanding its role in embryonic development is essential for developmental biology.

Purpose of the Study:

To clone the cDNA of Xenopus laevis vitronectin.
To investigate the spatial and temporal expression patterns of vitronectin during Xenopus embryonic development.

Main Methods:

cDNA cloning of Xenopus laevis vitronectin.
Analysis of deduced amino acid sequence identity with orthologs.
Spatial and temporal expression analysis using transcript and protein detection.

Main Results:

Xenopus laevis vn shares structural similarities with higher vertebrate vitronectins.
Vitronectin transcripts are detected from stage 28 onwards.
Vitronectin protein is found in the heart, liver, gut, pronephros, and notochord during tadpole stages.

Conclusions:

Vitronectin expression is developmentally regulated in Xenopus.
Vitronectin likely participates in the organogenesis of Xenopus embryos.