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Related Experiment Video

Updated: Jun 14, 2026

Real-Time Void Spot Assay

Real-Time Void Spot Assay

Published on: February 10, 2023

The relationship between children with voiding problems and their parents.

J Labrie¹, T P V M de Jong, A Nieuwhof-Leppink

¹Department of Perinatology and Gynecology, (University Children's Hospital), University Medical Center Utrecht, Utrecht, The Netherlands. j.labrie@umcutrecht.nl

The Journal of Urology

|March 23, 2010

Summary

Parents of children with overactive bladder (OAB) and dysfunctional voiding (DV) often experienced similar childhood urinary symptoms. These childhood OAB symptoms can persist into adulthood, suggesting a familial link in these conditions.

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Assessing the Coherence of Parents' Short Narratives Regarding their Child Using the Five-Minute Speech Sample Procedure

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Published on: September 19, 2019

Area of Science:

Pediatric Urology
Genetics and Heredity
Urogynecology

Background:

Overactive bladder (OAB) and dysfunctional voiding (DV) are common pediatric conditions.
The familial aggregation of these conditions is not well understood.

Purpose of the Study:

To investigate the prevalence of childhood urinary symptoms in parents of children diagnosed with OAB or DV.
To determine if there is a familial link between parental and pediatric lower urinary tract symptoms.

Main Methods:

A case-control study involving 173 parents of children with OAB/DV and 98 controls.
Parental childhood symptoms assessed via a 19-item questionnaire.
Current urogenital symptoms evaluated using the Urogenital Distress Inventory.

Main Results:

Mothers of children with OAB/DV reported significantly more childhood urinary symptoms than control mothers.
Childhood OAB symptoms showed persistence into adulthood.
Fathers of children with OAB stopped bed-wetting at a later age compared to controls.

Conclusions:

A significant association exists between childhood overactive bladder symptoms in children and their parents.
Dysfunctional voiding symptoms in children also show a familial association, though to a lesser extent.