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Repressing Gene Transcription by Redirecting Cellular Machinery with Chemical Epigenetic Modifiers
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Egr-1-A Ca(2+)-regulated transcription factor.

Gerald Thiel1, Sabine I Mayer, Isabelle Müller

  • 1Department of Medical Biochemistry and Molecular Biology, University of Saarland Medical Center, Homburg, Germany. gerald.thiel@uks.eu <gerald.thiel@uks.eu>

Cell Calcium
|March 23, 2010
PubMed
Summary

Extracellular signals boost Egr-1 gene transcription by increasing intracellular calcium (Ca2+). This calcium-regulated transcription factor plays a key role in cellular responses to various stimuli.

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