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Related Concept Videos

Influenza01:27

Influenza

Influenza is an acute, highly communicable viral disease that affects the respiratory tract and is responsible for seasonal epidemics worldwide. Influenza A is the most prevalent type associated with widespread outbreaks and is subtyped based on two surface glycoproteins: hemagglutinin (H) and neuraminidase (N), as in H1N1. These glycoproteins are essential for viral infectivity, transmission, and immune recognition. Transmission occurs primarily through respiratory droplets and contaminated...
Vaccinations01:51

Vaccinations

Overview
Infectious Diseases and Their Occurrence01:28

Infectious Diseases and Their Occurrence

Infectious diseases appear in populations through various transmission patterns, influenced by pathogen characteristics, population immunity, environmental conditions, and social behavior. Understanding these patterns is essential for effective public health surveillance and intervention. These categories—sporadic, outbreak, epidemic, pandemic, and endemic—help frame the nature and scope of disease events.Sporadic diseases occur irregularly and infrequently, without a predictable temporal or...
Respiratory Syncytial Virus Disease01:29

Respiratory Syncytial Virus Disease

Human respiratory syncytial virus (RSV) is a widespread pathogen that primarily targets infants and young children but also poses a serious health risk to elderly and immunocompromised individuals. Belonging to the Pneumoviridae family, RSV is a negative-sense, single-stranded RNA virus within the Pneumovirus genus. Its global health burden is significant, with millions of cases annually resulting in hospitalizations and mortality, particularly in resource-limited settings. Although most...
Acute Pharyngitis01:30

Acute Pharyngitis

Introduction
Acute pharyngitis is the inflammation of the back of the throat (pharynx), commonly resulting in a sore throat. It is a frequently encountered condition that prompts individuals to seek medical advice.
Classification
Acute pharyngitis can be categorized based on its underlying cause:
Arboviral Encephalitis01:25

Arboviral Encephalitis

Arboviral encephalitis refers to brain inflammation caused by arthropod-borne viruses, particularly those transmitted through mosquito vectors. Among these, West Nile virus (WNV), a member of the Flaviviridae family, is a significant public health concern. WNV is an enveloped, positive-sense, single-stranded RNA virus. Human infection typically begins when an infected mosquito introduces the virus into the dermis during feeding. The primary transmission cycle involves birds as amplifying hosts...

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Related Experiment Video

Updated: Jun 14, 2026

Development of Multiplex Real-Time RT-qPCR Assays for the Detection of SARS-CoV-2, Influenza A/B, and MERS-CoV
03:53

Development of Multiplex Real-Time RT-qPCR Assays for the Detection of SARS-CoV-2, Influenza A/B, and MERS-CoV

Published on: November 10, 2023

[Seasonal flu].

A Vabret1, J Dina, D Cuvillon-Nimal

  • 1Laboratoire de virologie, CHU de Caen, avenue Georges-Clémenceau, 14033 Caen, France. vabret-a@chu-caen.fr

Pathologie-Biologie
|March 23, 2010
PubMed
Summary
This summary is machine-generated.

Seasonal flu, caused by influenza A and B viruses, requires accurate diagnosis due to varied symptoms. Virological tests are crucial for identifying circulating strains and informing vaccine composition.

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A Luciferase-fluorescent Reporter Influenza Virus for Live Imaging and Quantification of Viral Infection

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Rapid Molecular Detection and Differentiation of Influenza Viruses A and B
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Rapid Molecular Detection and Differentiation of Influenza Viruses A and B

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Related Experiment Videos

Last Updated: Jun 14, 2026

Development of Multiplex Real-Time RT-qPCR Assays for the Detection of SARS-CoV-2, Influenza A/B, and MERS-CoV
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Development of Multiplex Real-Time RT-qPCR Assays for the Detection of SARS-CoV-2, Influenza A/B, and MERS-CoV

Published on: November 10, 2023

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A Luciferase-fluorescent Reporter Influenza Virus for Live Imaging and Quantification of Viral Infection

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Rapid Molecular Detection and Differentiation of Influenza Viruses A and B
05:38

Rapid Molecular Detection and Differentiation of Influenza Viruses A and B

Published on: January 30, 2017

Area of Science:

  • Virology
  • Epidemiology
  • Public Health

Context:

  • Seasonal influenza (flu) is caused by influenza A and B viruses, with subtypes defined by HA and NA glycoproteins.
  • It's an epidemic winter illness in temperate zones, characterized by significant viral variability.
  • Accurate diagnosis is challenging due to non-specific symptoms, especially in young children and the elderly.

Purpose:

  • To highlight the importance of virological testing for accurate influenza diagnosis.
  • To emphasize the need for an alert system to track circulating influenza variants.
  • To discuss available diagnostic methods for influenza detection in respiratory specimens.

Summary:

  • Influenza viruses A and B cause seasonal flu, featuring an RNA genome and surface glycoproteins HA and NA.
  • Diagnosis is complicated by non-specific symptoms, particularly in vulnerable populations like children and the elderly.
  • Virological tests, including cell culture, antigen detection, and RNA molecular detection, are essential for confirming influenza in hospitalized patients.

Impact:

  • Facilitates timely and accurate diagnosis of influenza, especially in vulnerable groups.
  • Informs annual vaccine composition by identifying dominant circulating strains.
  • Guides the selection of appropriate diagnostic methods based on sensitivity, specificity, speed, and cost.