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Updated: Jun 14, 2026

Localization of Plasma Membrane and Intracellular Neuronal Nicotinic Acetylcholine Receptors Using Quantitative Imaging in Mammalian Cells
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Localization of Plasma Membrane and Intracellular Neuronal Nicotinic Acetylcholine Receptors Using Quantitative Imaging in Mammalian Cells

Published on: December 19, 2025

Interaction of 18-methoxycoronaridine with nicotinic acetylcholine receptors in different conformational states

Hugo R Arias1, Avraham Rosenberg, Dominik Feuerbach

  • 1Department of Pharmaceutical Sciences, College of Pharmacy, Midwestern University, Glendale, Arizona, USA. harias@midwestern.edu

Biochimica Et Biophysica Acta
|March 23, 2010
PubMed

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Cholinergic agonists or cholinomimetics mimic the action of acetylcholine to stimulate the parasympathetic nervous system. They are categorized into direct-acting and indirect-acting agents. The direct-acting cholinergic drugs induce the parasympathetic response by directly binding to the muscarinic or nicotine receptors. In comparison, the indirect-acting cholinergic drugs prevent acetylcholine hydrolysis, indirectly contributing to the extended parasympathetic response.
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