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Analysis of Microglia and Monocyte-derived Macrophages from the Central Nervous System by Flow Cytometry
Published on: June 22, 2017
Severe cerebral vaso-occlusive disease in macrophage activation syndrome
Mohamad K El-Bitar1, Samar A Muwakkit, Rola Hourani
1Division of Pediatric Neurology and Pediatric Epilepsy Program, Department of Pediatrics, American University of Beirut Medical Center, 2020l Beirut, Lebanon.
Abstract:
A 14-year-old girl was diagnosed with macrophage activation syndrome, based on clinical presentation, laboratory tests, and bone marrow aspirate findings. She developed severe central nervous system involvement in the form of seizure disorder and severe diffuse occlusive cerebral vasculopathy, with extensive collateral circulation consistent with moyamoya disease. To our knowledge, this description is the first of these findings in association with macrophage activation syndrome.
