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Related Concept Videos

Aortic Regurgitation III: Medical Management01:25

Aortic Regurgitation III: Medical Management

Aortic regurgitation (AR) is when the aortic valve does not close or seal properly, leading to backward blood circulation from the aorta into the left ventricle during diastole. Common causes of AR include rheumatic heart disease, congenital valve defects, and aortic root dilation. Managing AR requires a multifaceted approach to alleviate symptoms, preserve left ventricular function, and address the underlying cause of the regurgitation. Patients with symptomatic AR or significant left...
Mitral Stenosis I: Introduction01:22

Mitral Stenosis I: Introduction

Mitral Valve Stenosis (MVS) is a heart condition where the mitral valve narrows, impeding blood circulation from the left atrium to the left ventricle. The etiology and pathophysiology of this condition are multifaceted, leading to a cascade of cardiovascular complications.Causes of Mitral Valve StenosisRheumatic Heart Disease: It is the main cause of mitral valve stenosis, particularly in developing nations. This condition arises from rheumatic fever, an inflammatory illness resulting from...
Aortic Regurgitation I: Introduction01:15

Aortic Regurgitation I: Introduction

IntroductionAortic regurgitation is characterized by the backward flow of blood from the aorta into the left ventricle during diastole and arises from the improper closure of the aortic valve. This condition results in left ventricular volume overload and can stem from both acute and chronic etiologies, each contributing uniquely to the disease's progression and symptomatology.Acute and Chronic CausesAcute aortic regurgitation often results from events that suddenly impair the integrity of the...
Mitral Stenosis III: Medical Management01:26

Mitral Stenosis III: Medical Management

Mitral stenosis, a condition marked by the narrowing of the mitral valve, necessitates an integrated approach for effective management. This approach includes preventative measures, medical therapy, and surgical interventions to reduce symptoms and prevent complications.PreventionPrevention of mitral stenosis primarily focuses on reducing the incidence of bacterial infections, particularly streptococcal infections, which can lead to rheumatic fever and subsequent valvular damage. Timely...
Mitral Valve Prolapse I: Introduction01:27

Mitral Valve Prolapse I: Introduction

IntroductionThe mitral valve, one of the heart's four valves, regulates blood flow. These valves have flaps that open and close to direct blood properly through the heart and body. During each heartbeat, the flaps open for blood to pass through and seal shut to prevent backflow. Specifically, the mitral valve opens to allow blood flow from the heart's upper left chamber to the lower left chamber. It then closes securely as the lower left chamber contracts to pump blood to the body, preventing...
Mitral Valve Prolapse II: Assessment and Management01:22

Mitral Valve Prolapse II: Assessment and Management

IntroductionA range of clinical features characterizes Mitral Valve Prolapse (MVP), but it is important to note that many individuals with MVP are asymptomatic and may remain so throughout their lives. For those who do exhibit symptoms, the following are the key clinical features:Palpitations: This is a common symptom where individuals feel an irregular or rapid heartbeat. Palpitations in MVP are often due to arrhythmias such as premature ventricular contractions or supraventricular tachycardia.

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Related Experiment Video

Updated: Jun 14, 2026

Technique and Patient Selection Criteria of Right Anterior Mini-Thoracotomy for Minimal Access Aortic Valve Replacement
08:50

Technique and Patient Selection Criteria of Right Anterior Mini-Thoracotomy for Minimal Access Aortic Valve Replacement

Published on: March 26, 2018

Primary isolated aortic valve surgery in octogenarians.

Enrico Ferrari1, Piergiorgio Tozzi, Michel Hurni

  • 1Department of Cardiovascular Surgery, University Hospital of Lausanne (CHUV), 46 rue du Bugnon, CH-1011, Lausanne, Switzerland. enricoferrari@bluewin.ch

European Journal of Cardio-Thoracic Surgery : Official Journal of the European Association for Cardio-Thoracic Surgery
|March 23, 2010
PubMed
Summary
This summary is machine-generated.

Octogenarians undergoing aortic valve replacement (AVR) surgery experience good short-term outcomes and satisfactory long-term survival rates. Open-heart surgery for AVR remains the standard of care for healthy elderly patients.

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Standardized Technique of Aortic Valve Re-implantation for Valve-sparing Aortic Root Replacement
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Full-root Aortic Valve Replacement by Stentless Aortic Xenografts in Patients with Small Aortic Roots
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Full-root Aortic Valve Replacement by Stentless Aortic Xenografts in Patients with Small Aortic Roots

Published on: May 21, 2017

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Last Updated: Jun 14, 2026

Technique and Patient Selection Criteria of Right Anterior Mini-Thoracotomy for Minimal Access Aortic Valve Replacement
08:50

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Published on: March 26, 2018

Standardized Technique of Aortic Valve Re-implantation for Valve-sparing Aortic Root Replacement
14:14

Standardized Technique of Aortic Valve Re-implantation for Valve-sparing Aortic Root Replacement

Published on: December 11, 2017

Full-root Aortic Valve Replacement by Stentless Aortic Xenografts in Patients with Small Aortic Roots
12:17

Full-root Aortic Valve Replacement by Stentless Aortic Xenografts in Patients with Small Aortic Roots

Published on: May 21, 2017

Area of Science:

  • Cardiovascular Surgery
  • Geriatric Cardiology
  • Valvular Heart Disease

Background:

  • Octogenarians represent a growing patient population undergoing cardiac procedures.
  • Aortic valve replacement (AVR) is a critical intervention for severe aortic stenosis in the elderly.
  • Assessing risks and long-term outcomes in this age group is essential for clinical decision-making.

Purpose of the Study:

  • To identify predictive risk factors for operative results in octogenarians undergoing primary isolated AVR.
  • To analyze the long-term survival outcomes in this patient cohort.
  • To evaluate the efficacy of open-heart AVR in elderly patients.

Main Methods:

  • Retrospective review of 124 consecutive octogenarians undergoing primary isolated AVR between 1990 and 2005.
  • Exclusion of combined procedures and redo surgeries.
  • Analysis of risk factors for hospital mortality and early neurological events, with Kaplan-Meier survival analysis (90% follow-up completion).

Main Results:

  • Observed hospital mortality was 5.6%, lower than the predicted 12.6% (logistic EuroSCORE).
  • Age at surgery and postoperative renal failure were predictors of hospital mortality.
  • Actuarial survival rates at 5 and 10 years were 88% and 50%, respectively, with a mean follow-up of 77 months.

Conclusions:

  • Primary isolated standard AVR in octogenarians yields good short-term results.
  • Aortic valve surgery in this age group ensures satisfactory long-term survival and quality of life.
  • Open-heart AVR remains the standard of care for healthy octogenarians, even with the advent of transcatheter alternatives.