Related Experiment Video
Updated: Jun 14, 2026

Understanding the Effects of Non-Invasive Transauricular Vagus Nerve Stimulation on EEG and HRV
Published on: January 19, 2024
Acupuncture and heart rate variability: a systematic review.
Sanghoon Lee1, Myeong Soo Lee, Jun-Yong Choi
1Department of Acupuncture and Moxibustion, College of Oriental Medicine, Kyung Hee University, Seoul, South Korea.
This systematic review found that sham-controlled randomized clinical trials (RCTs) show variable results regarding acupuncture's effect on heart rate variability (HRV). More rigorous research is needed to determine if acupuncture has specific effects on HRV.
Area of Science:
- Integrative and Complementary Medicine
- Cardiovascular Physiology
- Neuroscience
Background:
- Acupuncture is believed to influence the autonomic nervous system.
- Existing literature lacks systematic reviews on acupuncture's impact on heart rate variability (HRV).
Purpose of the Study:
- To systematically review and critically evaluate the effects of acupuncture on heart rate variability (HRV).
Main Methods:
- Conducted a literature search across 14 databases up to October 2009.
- Included randomized clinical trials (RCTs) comparing acupuncture with sham acupuncture.
- Assessed risk of bias using Cochrane criteria.
Main Results:
- Twelve RCTs met inclusion criteria, investigating acupuncture's effects in patients with depression, anxiety, migraine, and in healthy subjects under various conditions.
- Five RCTs reported significant HRV differences between acupuncture and sham acupuncture groups.
- The majority of RCTs showed inconsistent results or no significant differences in HRV parameters.
Conclusions:
- Sham-controlled RCTs on acupuncture and HRV yield variable results.
- There is no clear evidence for specific effects of acupuncture on HRV.
- Further high-quality research is warranted to clarify acupuncture's role in modulating HRV.
Related Concept Videos
Factors Influencing Heart Rate
Let us explore the significant factors affecting heart rate, including age, body temperature, posture, acute pain, chemical influences,...
Regulation of Heart Rates
The SNS increases heart rate through the release of norepinephrine and epinephrine, which act on beta-1 adrenergic receptors in the heart. This action increases the rate of depolarization in the sinoatrial (SA) node, the heart's...
Regulation of Pulse
Cardiac Output I:Effect of Heart Rate on Cardiac Output
Cardiac output (CO) refers to the total amount of blood ejected by one of the ventricles in liters per minute (L/min). In a resting adult, CO ranges from 5 to 6 L/min, adjusting according to the body's metabolic requirements.
Effect of Heart Rate on Cardiac Output
Cardiac output adapts to metabolic demands during stress, physical activity, or illness. The autonomic nervous system regulates heart rate via the sinoatrial node. The parasympathetic nervous system decreases heart rate...
