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Updated: Jun 14, 2026

Primary Outcome Assessment in a Pig Model of Acute Myocardial Infarction
Published on: October 14, 2016
Door-to-needle times in acute myocardial infarction
1Cardiology Department, Servergazi State Hospital, 3001 S Akasya Sitesi A Blok D 10, Bagbasi, Denizli, 20 225 Turkey. yaylalimd@gmail.com
Insights
Implementing a coordinated team approach significantly reduced door-to-needle times for ST-elevation myocardial infarction (STEMI) patients. This improved treatment accessibility and has the potential to enhance patient survival rates.
Area of Science:
- Cardiology
- Emergency Medicine
- Healthcare Management
Background:
- Thrombolytic therapy is crucial for acute ST-elevation myocardial infarction (STEMI).
- Timely treatment is critical for successful reperfusion in STEMI patients.
- Optimizing treatment pathways can improve patient outcomes.
Purpose of the Study:
- To evaluate the impact of an organized team approach on door-to-needle times in STEMI patients.
- To assess the effectiveness of enhanced communication and triage protocols.
- To determine if the new approach reduces treatment delays.
Main Methods:
- Prospective data collection on demographic, laboratory, and time interval data.
- Implementation of a team-based approach with trained personnel and specialized equipment.
- Direct communication between offsite cardiologists and pre-hospital emergency personnel.
- Triage of STEMI patients directly to the coronary care unit.
Main Results:
- Mean door-to-needle time decreased significantly from 80 to 30 minutes during regular hours.
- Mean door-to-needle time reduced from 85 to 33 minutes outside regular hours.
- Sixty STEMI patients were enrolled from April to December 2007, showing marked improvement over previous years.
Conclusions:
- A structured, team-based approach with trained staff and equipment effectively reduces door-to-needle times for STEMI.
- This model facilitates early evaluation and triage, leading to faster interventions.
- The strategy is broadly applicable and can improve patient survival in acute myocardial infarction cases.
Abstract:
Thrombolytic therapy is still the fastest and most accessible treatment for patients presenting with acute ST-elevation myocardial infarction. The time to treatment is a pivotal parameter in reperfusion. We examined the effects of implementing a better organized team approach to reduce door-to-needle times in patients with acute myocardial infarction. Fully trained emergency department personnel with special equipment facilitated direct communication between offsite cardiologists and pre-hospital emergency personnel, allowing for patient triage directly to the coronary care unit. Demographic, laboratory, and time interval data were prospectively collected and compared with data from previous years. From April to December 2007, 60 patients with acute ST-elevation myocardial infarction were triaged to the coronary care unit and enrolled in this study. Improvements were seen in mean door-to-needle time (reduced from 80 to 30 min during regular hours, and 85 to 33 min outside regular hours) compared with 2005-2007 data. A better organized team-based approach with specifically trained personnel and equipment for early evaluation and triage of patients with suspected myocardial infarction decreased intervention times, with the potential to be broadly applied in clinical practice and to improve patient survival.
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