Isolation and identification of ATP-secreting bacteria from mice and humans
Tadayuki Iwase1, Hitomi Shinji, Akiko Tajima
1Department of Bacteriology, The Jikei University School of Medicine, and Central Clinical Laboratory, Jikei University Hospital, 3-25-8, Nishi-shimbashi, Minato-ku, Tokyo, 105-8461 Japan. iwase.tadayuki@jikei.ac.jp
Journal of Clinical Microbiology
|March 23, 2010
Abstract:
In a recent report, ATP, which was possibly secreted by some intestinal bacteria, was shown to cause colitis in mice via Th17 cell differentiation. However, the ATP-secreting bacteria have not been isolated and identified. In the present study, we report that Enterococcus gallinarum, which is a vancomycin-resistant Gram-positive coccus isolated from mice and humans, secretes ATP.
