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HLA-D typing with an association of Dw2 and absent immune responses towards herpes simplex (type i) antigen in
Transplantation Proceedings
|December 1, 1977
Abstract:
We have confirmed that HLA-Dw2 is increased in MS patients to 47% (normals 20%). Lymphocyte transformation and antibody studies with herpes simplex antigen show that many of the DW2-positive MS patients have low or absent responses. The association of low responses to HSV and the presence of Dw2 is statistically significant at a p value less than 0.01.