Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Video

Updated: Jun 14, 2026

Three-Dimensional Reconstruction for the Whole Lung with Early Multiple Pulmonary Nodules
07:53

Three-Dimensional Reconstruction for the Whole Lung with Early Multiple Pulmonary Nodules

Published on: October 13, 2023

Lung nodule volumetry: segmentation algorithms within the same software package cannot be used interchangeably.

H Ashraf1, B de Hoop, S B Shaker

  • 1Department of Radiology, Gentofte Hospital, Copenhagen University, Hellerup, Denmark. Haseem@dadlnet.dk

European Radiology
|March 23, 2010
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Analysis of power law fluid for nutritional transport in the human capillary.

Computers in biology and medicine·2026
Same author

Unified Gait Event Detection using Temporal Convolutional Network and Bayesian Optimization.

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference·2025
Same author

Feasibility of a perioperative smartphone application in colorectal surgery.

The British journal of surgery·2021
Same author

Flow analysis of Carreau fluid model induced by the ciliary cells, smooth muscle cells and pressure gradient at the ampullar region entrance.

Theory in biosciences = Theorie in den Biowissenschaften·2021
Same author

Antiviral activities of Cholistani plants against common poultry viruses.

Tropical biomedicine·2021
Same author

Comparison effectiveness of acute coronary syndrome treatments on geriatric function.

Annales de cardiologie et d'angeiologie·2020

Lung nodule volumetry software showed poor reproducibility when different algorithms were used. Consistent algorithm selection is crucial for accurate lung nodule measurement in cancer screening.

Area of Science:

  • Medical Imaging
  • Radiology
  • Computational Pathology

Background:

  • Lung nodule volumetry is essential for lung cancer screening.
  • Accurate measurement of lung nodules aids in diagnosis and treatment planning.
  • Software-based volumetry aims to standardize and improve nodule measurement.

Purpose of the Study:

  • To assess the reproducibility of lung nodule volumetry software with multiple algorithms.
  • To compare inter-observer variability in nodule measurement using identical versus different algorithms.

Main Methods:

  • 188 baseline lung nodules (>5 mm) from a lung cancer screening trial were analyzed.
  • 545 nodules (including follow-ups) were segmented and measured by two independent readers.
  • Commercial volumetry software with three distinct algorithms was utilized.

More Related Videos

A 3D Digital Model for the Diagnosis and Treatment of Pulmonary Nodules
10:26

A 3D Digital Model for the Diagnosis and Treatment of Pulmonary Nodules

Published on: May 19, 2023

Using Computer Vision Libraries to Streamline Nuclei Quantification
06:25

Using Computer Vision Libraries to Streamline Nuclei Quantification

Published on: June 6, 2025

Related Experiment Videos

Last Updated: Jun 14, 2026

Three-Dimensional Reconstruction for the Whole Lung with Early Multiple Pulmonary Nodules
07:53

Three-Dimensional Reconstruction for the Whole Lung with Early Multiple Pulmonary Nodules

Published on: October 13, 2023

A 3D Digital Model for the Diagnosis and Treatment of Pulmonary Nodules
10:26

A 3D Digital Model for the Diagnosis and Treatment of Pulmonary Nodules

Published on: May 19, 2023

Using Computer Vision Libraries to Streamline Nuclei Quantification
06:25

Using Computer Vision Libraries to Streamline Nuclei Quantification

Published on: June 6, 2025

  • Inter-observer variability was compared based on algorithm selection.

    • Main Results:

    • Readers successfully segmented and measured 72% of nodules.
    • When using the same algorithm, 50% of measurements yielded identical volumes.
    • Using different algorithms resulted in >25% volume difference in 83% of cases.
    • Consistent algorithm use led to a >25% difference in only 4% of readings.

    Conclusions:

    • Current lung nodule volumetry software struggles with accurate segmentation of screen-detected nodules.
    • Using different algorithms significantly decreases the reproducibility of volumetric measurements.
    • Standardizing algorithm selection within the same software is critical for reliable follow-up measurements.