Related Experiment Video
Updated: Jun 14, 2026

07:50
A Metadata Extraction Approach for Clinical Case Reports to Enable Advanced Understanding of Biomedical Concepts
Published on: September 20, 2018
[Acquired methemoglobinemia--case report].
Anna Paczek1, Liliana Wawrzyńska, Ewa Mendek-Czajkowska
1Klinika Chorób Wewnetrznych Klatki Piersiowej, Instytut Gruźlicy i Chorób Płuc, ul. Płocka 26, Warsaw. anna.paczek@neostrada.pl
Pneumonologia I Alergologia Polska
|March 23, 2010
Summary
This case study highlights a 49-year-old man with unexplained cyanosis and dyspnea. His condition, diagnosed as methemoglobinemia, showed an elevated methemoglobin level of 16% and resolved spontaneously.
Area of Science:
- Hematology
- Internal Medicine
Background:
- Methemoglobinemia is a condition where hemoglobin's iron is oxidized, impairing oxygen transport.
- It can present with symptoms like cyanosis, dyspnea, and weakness, mimicking other cardiorespiratory diseases.
Observation:
- A 49-year-old male presented with dyspnea, weakness, and cyanosis.
- Pulmonary and cardiovascular causes were excluded through differential diagnosis.
- A significant "saturation gap" (low oxygen saturation with normal arterial oxygen tension) was noted.
Findings:
- Methemoglobinemia was diagnosed based on clinical presentation and a "saturation gap".
- Acute phase methemoglobin levels were elevated at 16%.
- The episode resolved spontaneously, with the underlying cause remaining undetermined.
Implications:
- This case underscores the importance of considering methemoglobinemia in patients with unexplained cyanosis and hypoxia.
- The "saturation gap" serves as a crucial diagnostic clue.
- Further investigation into the etiology of methemoglobinemia is warranted in similar cases.
