Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Pedigree Analysis01:35

Pedigree Analysis

Overview
Pleiotropy01:33

Pleiotropy

Pleiotropy is the phenomenon in which a single gene impacts multiple, seemingly unrelated phenotypic traits. For example, defects in the SOX10 gene cause Waardenburg Syndrome Type 4, or WS4, which can cause defects in pigmentation, hearing impairments, and an absence of intestinal contractions necessary for elimination. This diversity of phenotypes results from the expression pattern of SOX10 in early embryonic and fetal development. SOX10 is found in neural crest cells that form melanocytes,...
Incomplete Dominance01:43

Incomplete Dominance

Gregor Mendel's work (1822 - 1884) was primarily focused on pea plants. Through his initial experiments, he determined that every gene in a diploid cell has two variants called alleles inherited from each parent. He suggested that amongst these two alleles, one allele is dominant in character and the other recessive. The combination of alleles determines the phenotype of a gene in an organism.
Trihybrid Crosses02:27

Trihybrid Crosses

Trihybrid Crosses
Some of Mendel’s crosses examined three pairs of contrasting characteristics. Such a cross is called a trihybrid cross. A trihybrid cross is a combination of three individual monohybrid crosses. For example, plant height (tall vs. short), seed shape (round vs. wrinkled), and seed color (yellow vs. green).
The F1 generation plants of a trihybrid cross are heterozygous for all three traits and produce eight gametes. Upon self-fertilization, these gametes have an equal chance to...
Epistasis01:39

Epistasis

In addition to multiple alleles at the same locus influencing traits, numerous genes or alleles at different locations may interact and influence phenotypes in a phenomenon called epistasis. For example, rabbit fur can be black or brown depending on whether the animal is homozygous dominant or heterozygous at a TYRP1 locus. However, if the rabbit is also homozygous recessive at a locus on the tyrosinase gene (TYR), it will have an unshaded coat that appears white, regardless of its TYRP1...
Law of Segregation01:49

Law of Segregation

When crossing pea plants, Mendel noticed that one of the parental traits would sometimes disappear in the first generation of offspring, called the F1 generation, and could reappear in the next generation (F2). He concluded that one of the traits must be dominant over the other, thereby causing masking of one trait in the F1 generation. When he crossed the F1 plants, he found that 75% of the offspring in the F2 generation had the dominant phenotype, while 25% had the recessive phenotype.

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Social network analysis of tail-biting interactions among growing-finishing pigs with intact tails housed in two group sizes.

Journal of animal science·2026
Same author

Influence of group size on performance and tail biting in growing-finishing pigs with intact tails.

Animal welfare (South Mimms, England)·2026
Same author

Wipe Disinfection of Reusable Elastomeric Half-Mask Respirators for Health Care Use.

Workplace health & safety·2024
Same author

Experiences when using different EHMR models: Implications for different designs and meeting user expectations.

American journal of infection control·2024
Same author

Optimizing selection based on BLUPs or BLUEs in multiple sets of genotypes differing in their population parameters.

TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik·2024
Same author

Provider experiences with daily use of elastomeric half-mask respirators in health care.

American journal of infection control·2024

Related Experiment Video

Updated: Jun 14, 2026

Accurate and Phenol Free DNA Sexing of Day 30 Porcine Embryos by PCR
10:16

Accurate and Phenol Free DNA Sexing of Day 30 Porcine Embryos by PCR

Published on: February 14, 2016

Polydactyl inheritance in the pig.

Danielle Gorbach1, Benny Mote, Liviu Totir

  • 1Department of Animal Science and Center for Integrated Animal Genomics, Iowa State University, 2255 Kildee Hall, Ames, IA 50011, USA.

The Journal of Heredity
|March 24, 2010
PubMed
Summary

Polydactyly, an inherited disorder causing extra feet in pigs, was investigated. Genetic analysis suggests a recessive inheritance pattern, with a specific chromosome segment potentially influencing the trait.

More Related Videos

Quantification of Circulating Pig-Specific DNA in the Blood of a Xenotransplantation Model
07:34

Quantification of Circulating Pig-Specific DNA in the Blood of a Xenotransplantation Model

Published on: September 22, 2020

Related Experiment Videos

Last Updated: Jun 14, 2026

Accurate and Phenol Free DNA Sexing of Day 30 Porcine Embryos by PCR
10:16

Accurate and Phenol Free DNA Sexing of Day 30 Porcine Embryos by PCR

Published on: February 14, 2016

Quantification of Circulating Pig-Specific DNA in the Blood of a Xenotransplantation Model
07:34

Quantification of Circulating Pig-Specific DNA in the Blood of a Xenotransplantation Model

Published on: September 22, 2020

Area of Science:

  • Genetics
  • Animal Science
  • Veterinary Medicine

Background:

  • Polydactyly, characterized by extra digits, is an inherited disorder observed in various animal species.
  • Previous studies indicate polydactyly can be inherited through dominant or recessive genetic mechanisms.
  • The presence of preaxial polydactyly was noted in a purebred Yorkshire pig population.

Purpose of the Study:

  • To investigate the genetic basis of polydactyly in Yorkshire pigs.
  • To determine the mode of inheritance for this specific polydactyly trait.
  • To identify potential candidate genes and chromosomal regions associated with polydactyly.

Main Methods:

  • Experimental matings were performed using affected and unaffected pigs.
  • Candidate gene screening involved sequencing and linkage analysis for genes on SSC18.
  • A whole-genome scan using the Illumina PorcineSNP60 BeadChip was conducted on affected pigs and relatives.

Main Results:

  • Experimental matings suggested a recessive mode of inheritance, potentially with incomplete penetrance.
  • No significant association was found with candidate genes HOXA10-13, WNT2, and WNT16.
  • A 25-Mb homozygous region on SSC8 was identified as unique to the affected family, suggesting a potential role.

Conclusions:

  • The inheritance of polydactyly in this Yorkshire pig population appears to be recessive.
  • No major causative gene was identified through genome-wide association studies.
  • A specific chromosomal segment on SSC8 may contribute to polydactyly development in conjunction with other genetic factors.