Related Experiment Video
Updated: Jun 14, 2026

Optimized Management of Endovascular Treatment for Acute Ischemic Stroke
Published on: January 18, 2018
Second-opinion consultations in neuroradiology
Elcin Zan1, David M Yousem, Marco Carone
1The Russell H. Morgan Department of Radiology and Radiological Sciences, the Johns Hopkins Medical Institutions, 600 N Wolfe St, Phipps B-112, Baltimore, MD 21287, USA.
Second-opinion consultations for outside neuroradiology studies revealed a 7.7% discrepancy rate. These second opinions improved accuracy in 84% of cases where a definitive diagnosis was possible, benefiting patient care.
Area of Science:
- Radiology
- Medical Diagnostics
- Healthcare Policy
Background:
- Institutions increasingly utilize external imaging studies.
- Ensuring accuracy of outside interpretations is crucial for patient care.
- A policy for mandatory second-opinion consultations was implemented for external studies.
Purpose of the Study:
- To evaluate the clinical benefit of mandatory second-opinion consultations for external neuroradiology studies.
- To quantify the rate of interpretation discrepancies between outside reports and institutional second opinions.
Main Methods:
- Retrospective review of 7,465 outside neuroradiology studies from 2008.
- Comparison of outside reports with subspecialty neuroradiologist second-opinion reports.
- Classification of discrepancies using a five-point scale (clinically important vs. unimportant).
Main Results:
- Of 4,534 studies with comparison reports, 7.7% (347) had clinically important discrepancies.
- Discrepancies were more often in detection (67.1%) than interpretation (32.9%).
- Second opinions were correct in 84% of cases with category 4 or 5 discrepancies when a definitive diagnosis was available.
Conclusions:
- A significant rate of clinically important interpretation differences exists for outside neuroradiology studies.
- Mandatory second-opinion consultations identify critical discrepancies, enhancing diagnostic accuracy.
- Review of outside imaging studies by subspecialists demonstrably benefits patient care and clinical decision-making.
Related Concept Videos
Imaging Studies V: Intravenous Urography and Retrograde Pyelography
Radiological Investigation II: MRI and Ventilation Perfusion Scan
Magnetic Resonance Imaging (MRI) and Ventilation Perfusion Scans are two radiological investigations that offer detailed diagnostic images of the body, particularly lung structures.
MRI
MRI uses magnetic fields and radiofrequency signals to distinguish between normal and abnormal tissues. This technology provides a more detailed diagnostic image than CT scans, enabling it to characterize pulmonary nodules, stage bronchogenic carcinoma, and evaluate inflammatory activity in...
Imaging Studies I: CT and MRI
Description of the Procedures
Computed Tomography (CT) scan:
Computed Tomography (CT) scans use X-ray technology to generate detailed images of bones, organs, and tissues. During the scan, the patient lies on a moving table...
Radiological Investigation III: Pulmonary Angiogram and PET Scan
Pulmonary Angiogram
A Pulmonary Angiogram is an invasive procedure involving injecting a contrast medium through a catheter threaded into the pulmonary artery or the right side of the heart to visualize the pulmonary vasculature. Computed Tomography (CT) scans have mainly replaced this...
Imaging Studies VII: Vascular Imaging
Radiological Investigation I: X-ray and CT