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Updated: Jun 14, 2026

Modeling Spontaneous Metastatic Renal Cell Carcinoma (mRCC) in Mice Following Nephrectomy
Published on: April 29, 2014
How not to miss or mischaracterize a renal cell carcinoma: protocols, pearls, and pitfalls
Pamela T Johnson1, Karen M Horton, Elliot K Fishman
1The Russell H Morgan Department of Radiology and Radiologic Science, Johns Hopkins Hospital, 601 N Caroline St, Rm 3140D, Baltimore, MD 21287, USA. pjohnso5@jhmi.edu
Objective:
MDCT protocol optimization for renal cell carcinoma requires attention to several data acquisition, reconstruction, and display parameters. Specifically, multiple acquisitions with varying coverage, careful timing of each contrast-enhanced phase, and use of 2D and 3D multiplanar displays are required. This article reviews these parameters, supplemented by experience-based pearls and pitfalls.
Conclusion:
Proper data acquisition and utilization of postprocessing tools are essential to avoid missed diagnoses or misinterpretation when imaging renal cell carcinoma.
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