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Drug-Induced Sleep Endoscopy (DISE) with Target Controlled Infusion (TCI) and Bispectral Analysis in Obstructive Sleep Apnea
Published on: December 6, 2016
Sleep disordered breathing in children
Deepti Sinha1, Christian Guilleminault
1Stanford Hospital Sleep Disorders Clinic, Stanford University School of Medicine, Redwood City, CA, USA. bisther@yahoo.com
Insights
Sleep disordered breathing (SDB) in children, affecting 1-4%, stems from narrow airways and low muscle tone. Early diagnosis and treatment are crucial to prevent serious health issues like hypertension and learning difficulties.
Area of Science:
- Pediatric Pulmonology and Sleep Medicine
- Otolaryngology
- Genetics and Developmental Pediatrics
Background:
- Sleep disordered breathing (SDB) is a significant cause of morbidity in young children, with an estimated prevalence of 1-4%.
- Pediatric SDB arises from a combination of a structurally narrow airway, reduced neuromuscular tone, and increased airway collapsibility.
- SDB presentation and risk factors in children differ from adults, with higher prevalence in those with Down syndrome, midface hypoplasia, or neuromuscular disorders.
Purpose of the Study:
- To highlight the varied clinical presentations of SDB in children across different age groups.
- To emphasize the importance of diagnosing SDB in children due to its potential long-term health consequences.
- To outline current treatment modalities for pediatric SDB.
Main Methods:
- Review of clinical presentations and risk factors associated with pediatric SDB.
- Discussion of diagnostic considerations for SDB in the pediatric population.
- Overview of established and alternative treatment strategies for childhood SDB.
Main Results:
- Pediatric SDB symptoms range from snoring and arousals to enuresis and hyperactivity.
- Children with specific genetic or anatomical conditions are at increased risk.
- Untreated SDB can lead to learning difficulties, memory loss, hypertension, depression, and poor growth.
Conclusions:
- Prompt diagnosis of SDB in children is essential to mitigate adverse developmental and health outcomes.
- First-line treatment often involves tonsillectomy and adenoidectomy, with other options available.
- Effective management of pediatric SDB is critical for preventing long-term morbidity.
Abstract:
Sleep disordered breathing (SDB) is increasingly being recognised as a cause of morbidity even in young children. With an estimated prevalence of 1 to 4 per cent, SDB results from having a structurally narrow airway combined with reduced neuromuscular tone and increased airway collapsibility. SDB in children differs from adults in a number of ways, including presenting symptoms and treatment. Presentation may differ according to the age of the child. Children have a more varied presentation from snoring and frequent arousals to enuresis to hyperactivity. Those with Down syndrome, midface hypoplasia or neuromuscular disorders are at higher risk for developing SDB. First line definitive treatment in children involves tonsillectomy and adenoidectomy. Rapid maxillary expansion, allergy treatment and continuous positive airway pressure (CPAP) are other options. As untreated SDB results in complications as learning difficulties, memory loss and a long term increase in risk of hypertension, depression and poor growth, it is important to diagnose SDB.
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