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Published on: August 18, 2016
Personality and coronary heart disease
R B Shekelle1, S W Vernon, A M Ostfeld
1University of Texas School of Public Health, Houston.
Insights
Psychological distress, including neuroticism and somatic complaints, predicts uncomplicated angina but not heart attacks or coronary death. These traits may indicate a benign condition, not coronary heart disease itself.
Area of Science:
- Cardiology
- Psychological Medicine
- Epidemiology
Background:
- Psychological distress and personality traits are explored for their association with cardiovascular disease.
- Previous research has yielded mixed results regarding the link between psychological factors and coronary heart disease incidence and outcomes.
Purpose of the Study:
- To investigate the association between specific Minnesota Multiphasic Personality Inventory (MMPI) variables and the incidence of coronary heart disease (CHD) events.
- To examine the relationship between these psychological variables and the risk of coronary death following a myocardial infarction diagnosis.
Main Methods:
- A 10-year prospective cohort study involving 2003 middle-aged employed men.
- Assessment of three MMPI variables: HsK + Hy, neuroticism, and somatic complaints.
- Analysis of incidence of uncomplicated angina pectoris, myocardial infarction, and coronary death.
Main Results:
- HsK + Hy, neuroticism, and somatic complaints were positively associated with the incidence of uncomplicated angina pectoris.
- These psychological variables were not significantly associated with the incidence of myocardial infarction or coronary death.
- A negative association was found between these variables and the risk of coronary death after an angina diagnosis.
- HsK + Hy and somatic complaints were positively associated with the risk of coronary death in men who had previously survived a myocardial infarction.
Conclusions:
- Psychological distress and somatic complaints are linked to uncomplicated angina, a condition potentially distinct from atherosclerotic coronary heart disease.
- These traits may not increase the risk of developing coronary heart disease but could be associated with increased susceptibility to arrhythmias in individuals with existing ischemic myocardium.
Abstract:
Three MMPI variables--HsK + Hy, neuroticism, and somatic complaints--were positively associated with incidence of uncomplicated angina pectoris and not significantly associated with incidence of myocardial infarction and coronary death in a 10-year cohort study of 2003 employed middle-aged men. All three were negatively associated with risk of coronary death after the diagnosis of uncomplicated angina had been established. These results support the hypothesis that tendencies to report somatic complaints or to experience negative, distressing emotions chronically are not related to incidence of coronary heart disease but are associated with incidence of a relative benign, nonatherosclerotic condition that is similar clinically to angina pectoris. Also, HsK + Hy and somatic complaints were positively associated with risk of coronary death in men who had survived an initial myocardial infarction. This result does not indicate an association with coronary hearth disease itself because all of these men already had coronary heart disease. This result may indicate that the tendency to report somatic complaints is related to increased susceptibility to acute emotional stressors that can trigger arrhythmias in an ischemic myocardium.
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