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Related Experiment Videos

Can asthma be cured?

M Turner-Warwick1

  • 1Royal College of Physicians, London.

Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology
|January 1, 1991
PubMed
Summary
This summary is machine-generated.

Many individuals with asthma experience long-term symptom remission, suggesting a potential

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Area of Science:

  • Pulmonology and Respiratory Medicine
  • Immunology
  • Epidemiology

Background:

  • Asthma remission is observed in many patients, indicating potential for 'cure'.
  • The underlying mechanisms promoting the restoration of normal airway function are not fully understood.
  • Current asthma management strategies may influence the natural course of remission.

Purpose of the Study:

  • To explore the factors contributing to sustained asthma remission and 'cure'.
  • To investigate the role of environmental and biological factors in airway pathophysiology.
  • To evaluate the impact of anti-asthma medications on the development of inherent biological controlling factors for remission.

Main Methods:

  • Analysis of existing evidence on asthma remission.

Related Experiment Videos

  • Study of naturally occurring models of individuals in asthma remission versus those not.
  • Epidemiological data review concerning asthma prevalence, mortality, and medication use.
  • Main Results:

    • Asthma remission is a recognized phenomenon, but the factors driving it are complex and incompletely understood.
    • A multi-faceted approach is likely necessary for achieving asthma cure, involving reduction of inducers/sensitizers and stimulation of protective biological factors.
    • The potential impact of current asthma medications on inhibiting protective mechanisms requires urgent investigation, possibly explaining rising prevalence and mortality rates despite treatment advances.

    Conclusions:

    • Achieving asthma remission likely requires a comprehensive strategy targeting both external triggers and internal protective mechanisms.
    • Further research is crucial to understand how asthma medications influence the body's natural ability to achieve and maintain remission.
    • While the benefits of asthma treatment are clear, the potential unintended consequences on long-term remission warrant careful consideration and study.