University of Toronto

This paper outlines the protocol for qualitatively and quantitatively validating a university service-learning instrument, following the parsimony criterion to create the most robust and optimal version possible. The Delphi qualitative validation method and Robust Unweighted Least Squares Exploratory Factor Analysis, as a quantitative item optimization method, are utilized for this...

Presented here is a new version of expansion microscopy (ExM), Magnify, that is modified for up to 11-fold expansion, conserving a comprehensive array of biomolecule classes, and is compatible with a broad range of tissue types. It enables the interrogation of the nanoscale configuration of biomolecules using conventional diffraction-limited...

Source: Ketron Mitchell-Wynne, PhD, Asantha Cooray, PhD, Department of Physics & Astronomy, School of Physical Sciences, University of California, Irvine, CA
Legend states that Isaac Newton saw an apple fall from a tree. He noticed the acceleration of the apple and deduced that there must have been a force acting upon the apple. He then surmised that if gravity can act at the top of the tree, it can also act at even larger distances. He observed the motion of the moon and the orbits of...

This work presents a protocol to administrate Spanish Curriculum-Based Measures for the early detection of reading, math, and writing difficulties. These tools could help practitioners and applied researchers working in the context of the Response to Intervention...

This protocol describes an efficient electroporation method for the transfection of four different gastrointestinal organoid entities with larger plasmids (to the extent of 10 kB). It can be performed within one day and does not need extensive preparation or special, cost-intensive electroporation...

Light from astronomical objects must travel through the earth's turbulent atmosphere before it can be imaged by ground-based telescopes. To enable direct imaging at maximum theoretical angular resolution, advanced techniques such as those employed by the Robo-AO adaptive-optics system must be...