Related Experiment Video
Updated: Aug 20, 2026

Computed Tomography-guided Time-domain Diffuse Fluorescence Tomography in Small Animals for Localization of Cancer Biomarkers
Published on: July 17, 2012
Visualization and detection-localization on computed tomographic images
S E Seltzer1, R G Swensson, R D Nawfel
1Department of Radiology, Harvard Medical School, Brigham and Women's Hospital, Boston, Massachusetts 02115.
Abstract:
These studies investigated observers' ability to detect and locate highly visible liver lesions on computed tomographic (CT) images, manipulating both the lesion's location and polarity (brighter or darker than liver background). Visibility of a lesion is not sufficient to guarantee accurate localization. With clinical images, possible confusions between a lesion and coexisting normal structures (like blood vessels) is a serious constraint on observer performance.
More Related Videos
Related Concept Videos
Computed Tomography
The technique was invented in the 1970s and is based on the principle that as X-rays pass through the body, they are absorbed or reflected at different levels. In the technique, a patient lies on a motorized platform while a computerized axial tomography (CAT) scanner rotates...
Imaging Studies III: Computed Tomography

