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Embolic abscesses in hereditary hemorrhagic telangiectasia
1Department of Dermatology, University of Minnesota Hospitals, Minneapolis.
Journal of the American Academy of Dermatology
|April 1, 1991
Summary
Hereditary hemorrhagic telangiectasia (HHT) patients are at risk for embolic abscesses causing neurologic symptoms. Prophylactic antibiotics, similar to endocarditis protocols, are recommended for HHT patients undergoing procedures that may cause bacteremia.
Area of Science:
- Neurology
- Infectious Diseases
- Genetics
Background:
- Hereditary hemorrhagic telangiectasia (HHT) is an inherited vascular disorder.
- HHT is characterized by mucocutaneous telangiectases and visceral arteriovenous malformations.
- Patients with HHT face risks of serious clinical complications.
Observation:
- Two cases of HHT patients presenting with neurologic symptoms due to embolic abscesses are reported.
- One patient experienced a fatal outcome from this complication.
- The observed complication shares similarities with endocarditis in valvular heart disease patients.
Findings:
- Embolic abscesses can lead to severe neurologic complications in HHT patients.
- The incidence and microbiology of these abscesses resemble those seen in infective endocarditis.
- Prompt recognition and management of embolic events are crucial.
Implications:
- Patients with HHT may require enhanced vigilance for infectious complications.
- Consideration should be given to antibacterial prophylaxis for HHT patients.
- Prophylactic strategies should mirror those used for patients with valvular heart disease at risk for bacteremia.
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