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Clinical value of the tissue Doppler s wave to characterize left ventricular hypertrophy as defined by

Demian Chejtman1, Sergio Baratta, Horacio Fernández

  • 1Doppler-Echocardiography Section, Division of Cardiology, Hospital Universitario Austral, Perón 1500, B1629AHJ Pilar, Argentina. dchejtma@cas.austral.edu.ar

Echocardiography (Mount Kisco, N.Y.)
|March 25, 2010
PubMed

Insights

New Doppler ultrasound indices, isovolumic contraction (IC)/systolic wave (s) ratio and basal to mid-septal velocity difference (BMVD), can differentiate physiological left ventricular hypertrophy (LVH) from pathological forms. These parameters aid in distinguishing hypertrophic cardiomyopathy (HCM) from other causes of LVH.

Area of Science:

  • Cardiology
  • Medical Imaging
  • Physiology

Background:

  • Left ventricular hypertrophy (LVH) can be a normal physiological adaptation or a sign of various diseases with different prognoses.
  • Assessing regional myocardial function using color Doppler tissue imaging, particularly the isovolumic contraction (IC) period and systolic wave ("s"), is crucial.

Purpose of the Study:

  • To evaluate the utility of novel Doppler tissue imaging parameters in differentiating physiological from pathological LVH.
  • To distinguish between different subtypes of LVH, specifically hypertrophic cardiomyopathy (HCM) from other causes.

Main Methods:

  • Studied five groups: healthy young volunteers, healthy adult volunteers, athletes with LVH, hypertensive subjects with LVH, and subjects with HCM.
  • Measured peak "s" wave velocity, IC/s ratio, and basal to mid-septal velocity difference (BMVD) using color Doppler tissue imaging.

Main Results:

  • Significant differences in peak "s" wave velocity, IC/s ratio, and BMVD were observed across the studied groups (P < 0.0001).
  • An IC/s ratio < 0.38 demonstrated high sensitivity (90%) and specificity (88%) in discriminating physiological from pathological hypertrophy.
  • Peak "s" wave velocity and BMVD effectively identified HCM with high sensitivity and specificity.

Conclusions:

  • Peak "s" wave velocity, IC/s ratio, and BMVD are valuable novel parameters for distinguishing physiological from pathological LVH.
  • These indices can effectively differentiate between various subtypes of LVH, including HCM.
Abstract

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