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Related Concept Videos

Urine Studies I: Urinalysis01:29

Urine Studies I: Urinalysis

Urinalysis is a widely used diagnostic test that analyzes urine's physical, chemical, and microscopic characteristics. Healthcare providers use it to detect and monitor various health conditions, including renal disease, urinary tract infections (UTIs), diabetes, and metabolic or systemic disorders.Components of UrinalysisUrinalysis consists of three primary components: physical, chemical, and microscopic examination. Each provides unique insights into the urine sample and, by extension, the...

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Related Experiment Video

Updated: Jun 14, 2026

Hydrogel Nanoparticle Harvesting of Plasma or Urine for Detecting Low Abundance Proteins
10:05

Hydrogel Nanoparticle Harvesting of Plasma or Urine for Detecting Low Abundance Proteins

Published on: August 7, 2014

Urine collection and processing for protein biomarker discovery and quantification.

C Eric Thomas1, Wade Sexton, Kaaron Benson

  • 1Proteomics, H. Lee Moffitt Cancer Center, Tampa, FL 33612, USA.

Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology
|March 25, 2010
PubMed
Summary

Urine protein analysis offers a noninvasive method for disease biomarker discovery. Standardized protocols and new detection techniques enhance its utility for monitoring health and disease, particularly for cancer.

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Proteomic Profile of EPS-Urine through FASP Digestion and Data-Independent Analysis
14:48

Proteomic Profile of EPS-Urine through FASP Digestion and Data-Independent Analysis

Published on: May 8, 2021

Related Experiment Videos

Last Updated: Jun 14, 2026

Hydrogel Nanoparticle Harvesting of Plasma or Urine for Detecting Low Abundance Proteins
10:05

Hydrogel Nanoparticle Harvesting of Plasma or Urine for Detecting Low Abundance Proteins

Published on: August 7, 2014

Proteomic Profile of EPS-Urine through FASP Digestion and Data-Independent Analysis
14:48

Proteomic Profile of EPS-Urine through FASP Digestion and Data-Independent Analysis

Published on: May 8, 2021

Area of Science:

  • Biochemistry
  • Clinical Chemistry
  • Biomarker Discovery

Background:

  • Urine is a valuable, noninvasively collected biofluid for protein biomarker discovery.
  • It allows for monitoring diverse physiological processes and diseases.
  • Sufficient protein in urine aliquots supports multiple analyses using current and novel techniques.

Purpose of the Study:

  • To review the current state of urine collection, processing, and storage.
  • To assess methods for protein biomarker discovery and quantification in urine.
  • To highlight advancements relevant to cancer biomarker research.

Main Methods:

  • Review of existing literature and established protocols for urine sample handling.
  • Discussion of emerging protein detection and quantification technologies.
  • Comparison of traditional immunoassays with newer analytical methods.

Main Results:

  • Standardized protocols for urine collection and processing are under development.
  • New protein detection and quantification methods are emerging.
  • These advancements complement traditional immunoassays for biomarker analysis.

Conclusions:

  • Standardized urine collection, processing, and storage are crucial for reliable biomarker discovery.
  • Emerging protein quantification methods enhance the potential of urine as a diagnostic fluid.
  • These developments are particularly significant for the discovery and quantification of cancer biomarkers.