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Updated: Jun 14, 2026

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Published on: March 19, 2017
Pellagra: an old enemy of timeless importance
1Psychosomatic Medicine, Department of Psychiatry, Audie L. Murphy Memorial VAMC, San Antonio, TX 78229, USA. Thomas.brown5@va.gov
Background:
In the United States, pellagra is infrequently reported. Yet this disorder does occur among malnourished persons.
Objective:
The author seeks to clarify diagnosis and treatment.
Method:
The author describes various presentations and effects of this disorder.
Results:
Knowledge of classic and atypical presentations can assist in making the diagnosis. The author presents two cases of pellagra that exemplify the classic and atypical presentations.
Conclusion:
The typically robust response of the disorder to physiologic doses of niacin can assist in confirming the diagnosis.
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