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Published on: October 5, 2018
Wright and Fisher on inbreeding and random drift
1Genetics Laboratory, University of Wisconsin, Madison, Wisconsin 53706, USA. jfcrow@wisc.edu
Abstract:
Sewall Wright and R. A. Fisher often differed, including on the meaning of inbreeding and random gene frequency drift. Fisher regarded them as quite distinct processes, whereas Wright thought that because his inbreeding coefficient measured both they should be regarded as the same. Since the effective population numbers for inbreeding and random drift are different, this would argue for the Fisher view.
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