Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Restless Leg Syndrome and Night Terrors01:27

Restless Leg Syndrome and Night Terrors

Restless Leg Syndrome (RLS), also known as Willis-Ekbom disease, is a neurological disorder characterized by an uncontrollable urge to move the legs due to uncomfortable sensations. These sensations typically occur during periods of rest or inactivity, particularly when lying down or sitting, and can severely disrupt sleep.
The exact cause of RLS is not fully understood, but it is believed to involve dopamine, a neurotransmitter that helps regulate muscle movement. Imbalances in dopamine levels...
REM Sleep Behavior Disorder01:15

REM Sleep Behavior Disorder

REM Sleep Behavior Disorder (RBD) is a sleep disorder characterized by the absence of muscle paralysis that normally occurs during the REM phase of sleep. This absence allows individuals to physically act out their dreams, which are often vivid and disturbing. Common behaviors exhibited during episodes include kicking, punching, and yelling. These actions can be dangerous, potentially leading to injuries for the person with RBD or their bed partner.
RBD is significantly associated with...
Parkinson Disease l: Introduction01:24

Parkinson Disease l: Introduction

Parkinson’s disease is a chronic, progressive neurodegenerative disorder that primarily affects movement. It is characterized by motor symptoms such as resting tremors, muscle rigidity, bradykinesia (slowness of movement), and postural instability. Patients may notice hand tremors at rest, stiffness during movement, or a shuffling gait. In addition to motor features, non-motor symptoms include sleep disturbances, mood and behavioral changes, constipation, and cognitive impairment, all of which...
Alterations in Muscle Tone lll01:11

Alterations in Muscle Tone lll

Rigidity and myotonia are distinct abnormalities of muscle tone that affect resistance and relaxation during movement. Although both involve altered muscle contraction, they arise from different neurological and muscular mechanisms.CharacteristicsRigidity is characterized by uniform resistance to passive movement across the entire range, independent of speed, affecting flexors and extensors equally. It may appear as lead-pipe rigidity (smooth, constant resistance) or cogwheel rigidity...
Multiple Sclerosis l: Introduction01:19

Multiple Sclerosis l: Introduction

Multiple sclerosis is a chronic autoimmune disease of the central nervous system (CNS) that affects the brain, spinal cord, and optic nerves. It is an inflammatory demyelinating disorder and a leading cause of neurological disability in young adults.EpidemiologyMS commonly begins between 20 and 40 years of age and is twice as common in women. Its exact cause remains unclear, but genetic susceptibility contributes, with higher risk in first-degree relatives and identical twins. A greater...
Rocky Mountain Spotted Fever01:26

Rocky Mountain Spotted Fever

Rocky Mountain Spotted Fever (RMSF) is a severe tick-borne illness caused by Rickettsia rickettsii, a Gram-negative, coccobacillary bacterium. This pathogen is an obligate intracellular parasite, requiring a host cell for replication. Transmission occurs through the bite of an infected tick. In the United States, the most important vectors are Dermacentor variabilis (American dog tick) and Dermacentor andersoni (Rocky Mountain wood tick), though other tick species may also serve as vectors.

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Stridor Is an Independent Risk Factor for Mortality and Disease Progression in Patients with Multiple System Atrophy.

Movement disorders : official journal of the Movement Disorder Society·2025
Same author

Intensification of Diurnal Abnormal Movements During Sleep in Huntington's Disease.

Journal of Huntington's disease·2024
Same author

Genome sequence analyses identify novel risk loci for multiple system atrophy.

Neuron·2024
Same author

Care of Late-Stage Parkinsonism: Resource Utilization of the Disease in Five European Countries.

Movement disorders : official journal of the Movement Disorder Society·2024
Same author

Clinical and genetic keys to cerebellar ataxia due to FGF14 GAA expansions.

EBioMedicine·2023
Same author

Development and Validation of a Prognostic Model to Predict Overall Survival in Multiple System Atrophy.

Movement disorders clinical practice·2023

Related Experiment Video

Updated: Jun 14, 2026

Handwriting Analysis Indicates Spontaneous Dyskinesias in Neuroleptic Naïve Adolescents at High Risk for Psychosis
05:52

Handwriting Analysis Indicates Spontaneous Dyskinesias in Neuroleptic Naïve Adolescents at High Risk for Psychosis

Published on: November 21, 2013

[Restless legs syndrome epidemiology].

Imad Ghorayeb1, François Tison

  • 1Service des explorations fonctionnelles du système nerveux et de neurophysiologie clinique, hôpital Pellegrin, 33076 Bordeaux cedex, France. imad.ghorayeb@u-bordeaux2.fr

Presse Medicale (Paris, France : 1983)
|March 26, 2010
PubMed
Summary

Restless Legs Syndrome (RLS) is a chronic disorder causing an urge to move legs, often worsening at night. Increased awareness and education are crucial for accurate diagnosis and management of this common condition.

Area of Science:

  • Neurology
  • Sleep Medicine
  • Epidemiology

Background:

  • Restless Legs Syndrome (RLS) is a chronic sensorimotor disorder.
  • Characterized by an irresistible urge to move the legs, often with unpleasant sensations.
  • Symptoms worsen with rest, especially at night, and improve with activity.

Purpose of the Study:

  • To highlight the prevalence and characteristics of Restless Legs Syndrome.
  • To emphasize the need for improved diagnosis and education regarding RLS.
  • To underscore the importance of understanding RLS for effective therapeutic management.

Main Methods:

  • Review of existing epidemiological data and clinical associations of RLS.
  • Analysis of prevalence estimates in the Caucasian adult population.

More Related Videos

Behavioral Characterization of Pentylenetetrazole-induced Seizures: Moving Beyond the Racine Scale
07:35

Behavioral Characterization of Pentylenetetrazole-induced Seizures: Moving Beyond the Racine Scale

Published on: July 8, 2025

Quantifying Arms and Legs Contributions during Repetitive Electrically-Assisted Sit-To-Stand Exercise in Paraplegics: A Pilot Study
08:40

Quantifying Arms and Legs Contributions during Repetitive Electrically-Assisted Sit-To-Stand Exercise in Paraplegics: A Pilot Study

Published on: November 11, 2022

Related Experiment Videos

Last Updated: Jun 14, 2026

Handwriting Analysis Indicates Spontaneous Dyskinesias in Neuroleptic Naïve Adolescents at High Risk for Psychosis
05:52

Handwriting Analysis Indicates Spontaneous Dyskinesias in Neuroleptic Naïve Adolescents at High Risk for Psychosis

Published on: November 21, 2013

Behavioral Characterization of Pentylenetetrazole-induced Seizures: Moving Beyond the Racine Scale
07:35

Behavioral Characterization of Pentylenetetrazole-induced Seizures: Moving Beyond the Racine Scale

Published on: July 8, 2025

Quantifying Arms and Legs Contributions during Repetitive Electrically-Assisted Sit-To-Stand Exercise in Paraplegics: A Pilot Study
08:40

Quantifying Arms and Legs Contributions during Repetitive Electrically-Assisted Sit-To-Stand Exercise in Paraplegics: A Pilot Study

Published on: November 11, 2022

  • Identification of associated clinical conditions and demographic factors.

    • Main Results:

    • RLS prevalence ranges from 7.2% to 11.5% in Caucasian adults, increasing with age.
    • Women are more frequently affected than men; an 8.5% prevalence was estimated in France.
    • Associated conditions include pregnancy, iron deficiency, end-stage renal disease, and peripheral neuropathy.

    Conclusions:

    • RLS is often underdiagnosed, necessitating enhanced educational initiatives.
    • A comprehensive understanding of RLS is essential for appropriate diagnosis and treatment.
    • Improving RLS knowledge is a prerequisite for effective patient management.