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Baclofen intoxication after accidental ingestion in a 3-year-old child

Nagesh Dasarwar1, Preeti Shanbag, Nilesh Kumbhare

  • 1Pediatric Intensive Care Unit, Department of Pediatrics, Lokmanya Tilak Municipal Medical College and General Hospital, Sion, Mumbai - 400 022, India.

Indian Journal of Pharmacology
|March 26, 2010
PubMed

Insights

Accidental baclofen overdose in a child can cause severe symptoms like coma and low blood pressure. Prompt supportive care led to a full recovery, highlighting the need for parental education on baclofen toxicity.

Area of Science:

  • Pediatric Toxicology
  • Pharmacology
  • Neurology

Background:

  • Baclofen is a widely used skeletal muscle relaxant for spasticity.
  • Baclofen overdose cases are documented, but pediatric involvement is less common.
  • Accidental ingestion poses a risk, particularly in households with children.

Purpose of the Study:

  • To report a case of accidental baclofen overdose in a pediatric patient.
  • To highlight the clinical presentation and management of pediatric baclofen toxicity.
  • To emphasize the importance of safety precautions and parental counseling.

Main Methods:

  • Case report of a 3-year-old girl with accidental baclofen ingestion.
  • Clinical observation of presenting symptoms including coma, bradycardia, and hypotension.
  • Documentation of recovery following supportive medical treatment.

Main Results:

  • The patient presented with severe central nervous system depression and cardiovascular compromise.
  • Full recovery was achieved within 24 hours with intensive supportive care.
  • No long-term sequelae were observed.

Conclusions:

  • Accidental baclofen ingestion in children can lead to life-threatening symptoms.
  • Supportive treatment is effective in managing baclofen overdose.
  • Educating caregivers about baclofen's toxicity is crucial for preventing accidental pediatric exposures.

Keywords:
Accidental ingestionbaclofentoxicity

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