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Lumped-Parameter and Finite Element Modeling of Heart Failure with Preserved Ejection Fraction

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[Design and control of a simulating cardiovascular system].

Yi Liu¹, Ming Yang, Shiyang Li

¹Department of Instruments Science and Engineering, Shanghai Jiaotong University, Shanghai 200240, China. richieliu@sjtu.edu.cn

Sheng Wu Yi Xue Gong Cheng Xue Za Zhi = Journal of Biomedical Engineering = Shengwu Yixue Gongchengxue Zazhi

|March 27, 2010

Summary

This study introduces a novel simulating device to assess artificial hearts and cardiac assist devices. The device accurately mimics cardiovascular hemodynamics, enabling better evaluation of these critical medical technologies.

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Area of Science:

Biomedical Engineering
Cardiovascular Physiology
Medical Device Simulation

Context:

Evaluating artificial hearts and cardiac assist devices requires accurate hemodynamic assessment.
Existing methods may not fully capture the complex dynamics of the cardiovascular system.
Compression cardiac assist devices necessitate specialized simulation tools.

Purpose:

To develop a simulating device capable of imitating the cardiovascular system.
To create an algorithm for generating pressure-volume loops from measured parameters.
To validate the device's ability to represent physiological conditions.

Summary:

A simulating device comprising a pump, valve, tubes, and controller was engineered to mimic cardiovascular hemodynamics.
An algorithm was developed to generate pressure-volume loops using liquid pressure, volume, and air pressure data.
The device effectively simulates varying heart rates, systole periods, and physiological levels by adjusting control signals and valve angles.

Impact:

The developed simulating device provides a valuable tool for studying cardiovascular hemodynamics.
Experimental results from the device align with established physiological data.
This research aids in the evaluation and advancement of artificial heart and cardiac assist technologies.