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Is eosinophilic ureteritis an entity? 2 case reports and review
R P Spark1, D M Gleason, C D DeBenedetti
1Department of Pathology, Tucson Medical Center, Arizona 85733.
The Journal of Urology
|June 1, 1991
Summary
Eosinophilic ureteritis and idiopathic segmental ureteritis present distinct clinical and pathological features, despite overlapping symptoms. This study clarifies their separation, aiding in accurate diagnosis and treatment of ureteral obstruction.
Area of Science:
- Urology
- Pathology
- Immunology
Background:
- Eosinophilic ureteritis and idiopathic segmental ureteritis share overlapping characteristics, posing a diagnostic challenge.
- Distinguishing between these two ureteral conditions is crucial for appropriate patient management.
Observation:
- This study compared two new cases of eosinophilic ureteritis with eight previous reports and twenty-one cases of idiopathic segmental ureteritis.
- Eosinophilic ureteritis was noted to occur in atopic or hypereosinophilic syndromes, often with a history of trauma.
- Unique cases included renal pelvic involvement, a 3-year-old patient, and bilateral eosinophilic ureteritis.
Findings:
- Both conditions cause ureteral obstruction via mural involvement.
- Eosinophilic ureteritis is characterized by the absence of intraluminal mass formation and mucosal ulceration.
- No reported cases demonstrated features bridging eosinophilic and idiopathic segmental ureteritis.
Implications:
- The distinct clinical and pathological features support the separation of eosinophilic ureteritis and idiopathic segmental ureteritis as distinct nosological entities.
- This differentiation can improve diagnostic accuracy and guide targeted therapeutic strategies for ureteral obstructive diseases.
- Further research into the specific etiologies and pathomechanisms of each condition is warranted.