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Related Concept Videos

Glaucoma: Overview01:25

Glaucoma: Overview

Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
Angle Closure Glaucoma: Treatment01:28

Angle Closure Glaucoma: Treatment

Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
Open Angle Glaucoma: Treatment01:27

Open Angle Glaucoma: Treatment

In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
Photoreceptors and Visual Pathways01:22

Photoreceptors and Visual Pathways

At the molecular level, visual signals trigger transformations in photopigment molecules, resulting in changes in the photoreceptor cell's membrane potential. The photon's energy level is denoted by its wavelength, with each specific wavelength of visible light associated with a distinct color. The spectral range of visible light, classified as electromagnetic radiation, spans from 380 to 720 nm. Electromagnetic radiation wavelengths exceeding 720 nm fall under the infrared category, whereas...

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Related Experiment Video

Updated: Jun 14, 2026

A Model of Glaucoma Induced by Circumlimbal Suture in Rats and Mice
07:00

A Model of Glaucoma Induced by Circumlimbal Suture in Rats and Mice

Published on: October 5, 2018

Nasal Retinoschisis Associated with Glaucoma.

Jean-Pierre Hubschman, Shantan Reddy, Andrew Kaines

    Ophthalmic Surgery, Lasers & Imaging : the Official Journal of the International Society for Imaging in the Eye
    |March 27, 2010
    PubMed
    Summary

    This study reports nasal and macular retinoschisis in a patient with open-angle glaucoma. Glaucoma-related structural defects may explain the retinoschisis, suggesting an alternative to congenital optic nerve head pits.

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    Related Experiment Videos

    Last Updated: Jun 14, 2026

    A Model of Glaucoma Induced by Circumlimbal Suture in Rats and Mice
    07:00

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    Published on: October 5, 2018

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    08:30

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    Published on: March 12, 2016

    A Magnetic Microbead Occlusion Model to Induce Ocular Hypertension-Dependent Glaucoma in Mice
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    A Magnetic Microbead Occlusion Model to Induce Ocular Hypertension-Dependent Glaucoma in Mice

    Published on: March 23, 2016

    Area of Science:

    • Ophthalmology
    • Retinal Diseases
    • Glaucoma Research

    Background:

    • Open-angle glaucoma can cause structural damage to the optic nerve head.
    • Retinoschisis, the splitting of the retinal layers, can occur in various retinal conditions.
    • The etiology of retinoschisis can be multifactorial, including congenital and acquired causes.

    Purpose of the Study:

    • To describe a unique case of nasal and macular retinoschisis in a patient with pre-existing open-angle glaucoma.
    • To investigate potential causes for the development of retinoschisis in the absence of other identifiable factors.
    • To propose a link between glaucoma-induced optic nerve head abnormalities and the occurrence of retinoschisis.

    Main Methods:

    • Case report of a 75-year-old female patient.
    • Clinical examination and imaging (details not specified in abstract).
    • Differential diagnosis to exclude other causes of retinoschisis.

    Main Results:

    • The patient presented with both macular and nasal retinoschisis.
    • No other identifiable causes for the retinoschisis were found.
    • The patient had pre-existing optic nerve head damage from chronic open-angle glaucoma.

    Conclusions:

    • Glaucoma-related structural defects of the optic nerve head are a plausible cause for the observed retinoschisis.
    • This case suggests that glaucoma may contribute to the formation of retinoschisis cavities.
    • The findings challenge the assumption of multiple occult congenital pits of the optic nerve head as the sole explanation for such presentations.