Related Experiment Video
Updated: Jun 14, 2026

05:33
Ear Plaster Therapy as a Safe and Effective Treatment for Gestational Vomiting
Published on: August 4, 2023
Bilious vomiting in the newborn: 6 years data from a Level III Centre
Atul Malhotra1, Anil Lakkundi, Elizabeth Carse
1Monash Newborn, Monash Medical Centre, Melbourne, Australia. atul_m75@yahoo.com
Journal of Paediatrics and Child Health
|March 27, 2010
Summary
Bilious vomiting in newborns requires prompt surgical evaluation. Contrast imaging is a reliable diagnostic tool, with a high positive predictive value for identifying surgical conditions in neonates.
Area of Science:
- Neonatal Surgery
- Pediatric Surgery
- Diagnostic Imaging
Background:
- Bilious vomiting in newborns is a critical condition necessitating prompt neonatal and pediatric surgical intervention.
- Standard investigations include abdominal X-ray and contrast imaging.
- This study evaluates surgical intervention rates and contrast imaging accuracy for neonatal bilious vomiting.
Purpose of the Study:
- To determine the prevalence of surgical intervention in newborns with bilious vomiting.
- To assess the reliability of contrast imaging in predicting the underlying surgical condition.
Main Methods:
- Retrospective audit of data from a level III unit (December 2001 - October 2007).
- Included newborns admitted with bilious vomiting; excluded those with bilious aspirates but no vomiting.
- Analyzed data on demographics, investigations (X-ray, contrast studies), and surgical outcomes.
Main Results:
- Sixty-one infants with bilious vomiting were analyzed; 85.2% had abnormal X-rays and 34.4% had abnormal contrast studies.
- Surgical intervention (laparotomy) was performed in 26.6% of cases, revealing conditions like malrotation with volvulus, small bowel obstruction, and Hirschsprung's disease.
- Barium contrast studies demonstrated a positive predictive value of 85.7% for accurate surgical findings.
Conclusions:
- Bilious vomiting in neonates is a surgical emergency requiring urgent investigation.
- Contrast studies remain a cornerstone in diagnosing the underlying surgical pathology.
Related Concept Videos
Pathophysiology of Vomiting
Vomiting is a complex physiological response to expel harmful or irritating substances from the body. It's a defensive mechanism triggered by stimuli like poisons, microbial toxins, cytotoxic drugs, and mechanical abdominal distension. The process is centrally coordinated by the vomiting (or emetic) center located in the medulla of the brainstem. This area, rich in muscarinic M1, histamine H1, neurokinin 1 (NK1), and serotonin 5-HT3 receptors, coordinates the act of vomiting through interaction...
Pharmacokinetics in Pediatric Patients: Overview and Drug Absorption
Understanding the physiological differences in the pediatric population is crucial for effective pharmacotherapy. Neonates, infants, and children exhibit significant variations in gastric pH, gastric emptying time, intestinal transit time, and biliary function. These variations profoundly affect oral drug absorption, necessitating a nuanced approach to pediatric dosing.Neonates present with a unique physiological profile, having a gastric pH greater than 4 and faster and more irregular gastric...
Aneurysm IV: Nursing Management
Vigilant monitoring for aneurysm rupture is essential for patients undergoing aortic surgery.Preoperative Nursing ManagementContinuously monitor the patient for manifestations of aneurysm rupture, such as pallor, weakness, tachycardia, hypotension, abdominal, back, groin, or periumbilical pain, changes in consciousness, and a pulsating abdominal mass. Regularly assess the patient's peripheral pulses.Instruct the patient to consume a clear liquid diet the day before surgery and administer...
Bacterial Gastroenteritis
Bacterial gastroenteritis, characterized by diarrhea, abdominal cramps, and vomiting, is often caused by ingestion of contaminated food or water and is frequently associated with pathogenic Escherichia coli strains. These microbes exploit two principal mechanisms to inflict disease.Shiga toxin–producing E. coli, also referred to as STEC—notably O157:H7—release Shiga toxins that target ribosomes, blocking protein synthesis. The B subunit of the toxin binds the host glycolipid receptor...
Pyloric Obstruction
Pyloric obstruction, also referred to as gastric outlet obstruction, is a condition characterized by narrowing or blockage at the pylorus—the muscular valve regulating the flow of stomach contents into the duodenum. When this passage becomes impaired, the stomach cannot effectively empty its contents into the small intestine. This disruption leads to a range of gastrointestinal symptoms, including early satiety, bloating, epigastric pain, postprandial nausea, persistent vomiting, and...