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Related Experiment Video

Updated: Jun 14, 2026

Micro-dissection of Enamel Organ from Mandibular Incisor of Rats Exposed to Environmental Toxicants
08:12

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Published on: March 29, 2018

Explaining gender differences in caries: a multifactorial approach to a multifactorial disease.

Maria Ferraro1, Alexandre R Vieira

  • 1Department of Oral Biology, School of Dental Medicine, University of Pittsburgh, Pittsburgh, PA 15261, USA.

International Journal of Dentistry
|March 27, 2010
PubMed
Summary

Women experience higher rates of dental caries due to factors like salivary differences, hormonal changes, and genetics. Further research is needed to explore other potential contributing factors to this disparity.

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Systematic Approach to Identify Novel Antimicrobial and Antibiofilm Molecules from Plants' Extracts and Fractions to Prevent Dental Caries
08:20

Systematic Approach to Identify Novel Antimicrobial and Antibiofilm Molecules from Plants' Extracts and Fractions to Prevent Dental Caries

Published on: March 31, 2021

Area of Science:

  • Dental Public Health
  • Oral Biology
  • Epidemiology

Background:

  • Caries prevalence is notably higher in women compared to men.
  • Understanding the multifactorial nature of caries is crucial for targeted prevention strategies.

Purpose of the Study:

  • To investigate and elucidate the specific factors contributing to the higher incidence of caries in women.
  • To compare and contrast caries risk factors between men and women.

Main Methods:

  • Systematic review of existing literature on caries etiology.
  • Analysis of factors including salivary composition, hormonal fluctuations, diet, genetics, and systemic diseases.
  • Comparison of risk factor prevalence and impact between genders.

Main Results:

  • Women exhibit distinct salivary composition and flow rates influencing caries risk.
  • Hormonal fluctuations, specific dietary habits, genetic predispositions, and social roles are identified as significant risk factors for women.
  • Systemic diseases linked to caries show a greater association with the female gender.

Conclusions:

  • The higher caries rates in women are attributed to a complex interplay of biological, behavioral, and social factors.
  • Factors such as altered salivary parameters, hormonal influences, and genetic variations contribute significantly.
  • Further investigation is warranted to explore the potential, yet unproven, roles of oral microflora and exposure duration in female caries development.