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07:01
An Orthotopic Mouse Model of Anaplastic Thyroid Carcinoma
Published on: April 17, 2013
Papillary type thyroid carcinoma in an ovarian struma
J P O'Neill1, P Burns, J Kinsella
1The Department of Otolaryngology, Head and Neck Surgery, St James Hospital, Dublin, Ireland. joneill@rcsi.ie
Irish Journal of Medical Science
|March 27, 2010
Summary
Malignant struma ovarii, a rare ovarian teratoma with thyroid tissue, can transform into cancer. This case highlights the need for surgical removal and thyroid gland excision for monitoring.
Area of Science:
- Gynecologic Oncology
- Endocrinology
- Pathology
Background:
- Struma ovarii are germ cell tumors originating from ectopic thyroid tissue within ovarian teratomas.
- Malignant transformation of struma ovarii is exceptionally rare, occurring in 1-2% of cases, and can present as thyroid carcinoma.
Observation:
- A 22-year-old female presented with symptoms suggestive of a pelvic mass.
- Diagnostic imaging revealed a significant right pelvic mass, prompting surgical intervention.
Findings:
- Laparoscopic salpingo-oophrectomy confirmed a diagnosis of malignant struma ovarii.
- Histopathological examination identified thyroidal malignancy within the ovarian teratoma.
Implications:
- Surgical extirpation of the ovarian mass is crucial for managing malignant struma ovarii.
- Total thyroidectomy is recommended post-diagnosis to facilitate accurate thyroglobulin monitoring for potential recurrence.
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