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Updated: Jun 14, 2026

Bone Marrow Transplantation Platform to Investigate the Role of Dendritic Cells in Graft-versus-Host Disease
Published on: March 17, 2020
[Chronic graft-versus-host disease: a multidisciplinary approach]
Chronic Graft-Versus-Host Disease (GVHD) is a common complication after stem cell transplants. Recent advancements have improved its classification and treatment strategies for better patient outcomes.
Area of Science:
- Hematology
- Immunology
- Oncology
Context:
- Allogeneic hematopoietic cell transplantation (HCT) is a curative therapy for various hematologic malignancies and genetic disorders.
- Chronic Graft-Versus-Host Disease (GVHD) remains a significant challenge, impacting long-term patient survival and quality of life post-HCT.
Purpose:
- This review synthesizes recent developments in understanding and managing chronic GVHD.
- To provide an updated overview of diagnostic criteria and therapeutic approaches for chronic GVHD.
Summary:
- Recent studies have refined the classification criteria for chronic GVHD, enabling more precise diagnosis.
- Novel therapeutic strategies targeting specific immune pathways and inflammatory processes have emerged, showing promise in early trials.
Impact:
- Improved diagnostic accuracy facilitates earlier intervention and personalized treatment plans for chronic GVHD.
- Advances in treatment offer hope for mitigating the severity and long-term consequences of chronic GVHD, enhancing patient recovery and survival post-HCT.
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09:50Induction of Intestinal Graft-versus-host Disease and Its Mini-endoscopic Assessment in Live Mice
Published on: February 11, 2019
06:06Induction and Scoring of Graft-Versus-Host Disease in a Xenogeneic Murine Model and Quantification of Human T Cells in Mouse Tissues using Digital PCR
Published on: May 23, 2019
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