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[Digital clubbing]

D Salerno1, J Delwaide, O Detry

  • 1Université de Liège, Belgique.

Revue Medicale De Liege
|March 30, 2010
PubMed

Insights

Digital clubbing, a long-known clinical sign, lacks a complete explanation for its primary and secondary forms. This review explores current hypotheses and associated pathologies, focusing on lung, digestive diseases, and cirrhosis, to advance understanding and potential treatments.

Area of Science:

  • Medical Sciences
  • Clinical Medicine
  • Pathophysiology

Context:

  • Digital clubbing is a recognized clinical manifestation with unknown underlying mechanisms.
  • The phenomenon presents in primary and secondary forms, often linked to various systemic diseases.
  • Existing theories do not fully elucidate the pathophysiology of digital clubbing.

Purpose:

  • To review current hypotheses explaining the phenomenon of digital clubbing.
  • To explore the association between digital clubbing and prevalent pathologies.
  • To highlight the role of pulmonary and digestive diseases, including cirrhosis, in digital clubbing.

Summary:

  • This article synthesizes contemporary theories on digital clubbing.
  • It examines the link between digital clubbing and key conditions such as pulmonary and digestive pathologies.
  • Cirrhosis is specifically discussed as a significant associated condition.

Impact:

  • Understanding the mechanisms of digital clubbing could pave the way for novel therapeutic strategies.
  • This review aims to consolidate knowledge on digital clubbing pathophysiology.
  • Further research into these mechanisms may lead to effective treatments for patients presenting with digital clubbing.

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