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Sublingual Immunotherapy as an Alternative to Induce Protection Against Acute Respiratory Infections
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[Clinical experience with subcutaneous immunoglobulin administration in the treatment of primary immunodeficiencies]

M Delire1, M O Bleuze, P E Baugnée

  • 1Laboratoire du Dr Collard, Liège, Belgique. delirem00@yahoo.co.uk

Revue Medicale De Liege
|March 30, 2010
PubMed

We report the clinical evolution of three adult patients with recurrent respiratory tract infections. Those patients had a low plasma level of IgG3 and/or a deficiency in anti polysaccharide antibodies. They all were previously treated with intravenous immunoglobulin, but their clinical status as well as their health related quality of life improved after they had switched to subcutaneous immunoglobulin administrations. The frequency of subcutaneous injections was on a weekly basis and the dosage was adjusted in order to reach the cumulative monthly dose of intravenous infusions. The tolerance of the subcutaneous route of immunoglobulin injection was recorded as excellent in all three patients.

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