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Decreased expression of PRDM2 (RIZ1) and its correlation with risk stratification in patients with myelodysplastic

Wei Xie, Xiaoqing Li, Xiangjun Chen

    British Journal of Haematology
    |March 30, 2010
    PubMed
    Abstract

    No abstract available in PubMed .

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    Under normal conditions, most adult cells remain in a non-proliferative state unless stimulated by internal or external factors to replace lost cells. Abnormal cell proliferation is a condition in which the cell's growth exceeds and is uncoordinated with normal cells. In such situations, cell division persists in the same excessive manner even after cessation of the stimuli, leading to persistent tumors. The tumor arises from the damaged cells that replicate to pass the damage to the daughter...